Genes associated with “GSDMB”

1153 genes foundOpen Targets: cervical squamous intraepithelial neoplasia13 ClinVar P/LP variants
How are genes scored? (0–100 composite)
-5–15
ClinGen
0–15
HPO Freq
0–15
Open Targets
0–12
Phen2Gene
0–10
ClinVar
0–8
Constraint
0–8
Dosage
0–8
OMIM CS
0–8
PanelApp
0–5
OMIM
0–5
G2P
0–4
Breadth
Tiers:Strong Candidates (≥20)Consider (≥8)Possible (≥3)
Evidence dots:
HPOClinVarPhen2GeneOpen TargetsPanelApp
hover for details

Consider

670 genes
19GSDMB

gasdermin B

15COL1A1
Def
15EFTUD2
Def
15HNF1B
Def
15KANSL1
Def
15NOG
Def
14AXIN2
Def
14BPTF
Def
14RAD51C
Def
14RAD51D
Def
14TBX4
Def
14LSM12
14LUC7L3
14MBTD1
14MED1
14MEIOC
14MLLT6
14TP53
DefSF

tumor protein p53

13BRCA1
DefSF
13CAVIN1
Def
13DGKE
Def
13DNAAF19
Def
13G6PC1
Def
13G6PC3
Def
13GFAP
Def
13GOSR2
Def
13GPR179
Def
13GRN
Def
13GSDMA

GASDERMIN A; GSDMA

13ITGA2B
Def
13ITGA3
Def
13ITGB3
Def
13MKS1
Def
13NAGLU
Def
13NAGS
Def
13NF1
Def
13ODAD4
Def
13PEX12
Def
13PGAP3
Def
13PNPO
Def
13RNF43
Def
13SGCA
Def
13SMARCE1
Def
13SOX9
Def
13SPOP
Def
13STAT3
Def
13STAT5B
Def
13TAOK1
Def
13TCAP
Def
13TUBG1
Def
13UBTF
Def
12ACE
Def
12BRIP1
Def
12CD79B
Def
12LIG3
Def
12MED13
Def
12PPM1D
Def
12PSMD12
Def
12SCN4A
Def
12SMG8
Def
12TACO1
Def
12TANC2
Def
12TLK2
Def
12TRIM37
Def
12NR1D1

nuclear receptor subfamily 1 group D member 1

12GAS2L2
Mod
12IKZF3
Mod
12MAP3K14
Mod
12PCGF2
Str
12PLEKHM1
Mod
12SLFN14
Mod
11DLG4
Def
11PMP22
Def
11RAI1
Def
11RGS9
Mod
11CDC6
Lim
11COA3
Lim
11COX11
Lim
11DNAI2
Def
11DNAJC7
Lim
11FDXR
Def
11FOXN1
Def
11KCNJ16
Def
11NEK8
Def
11PHF12
Def
11PIGS
Def
11PIGW
Lim
11PRKAR1A
Def
11TAF15
Lim
11USH1G
Def
10SPAG5

sperm associated antigen 5

10RPS6KB1
Lim
10AARSD1
10ABCC3
10ABI3
10ACACA
10ACBD4
10ACSF2
10ADAM11
10AKAP1
10ANKFN1
10ANKRD40
10AOC2
10AOC3
10AP2B1
10ARHGAP23
10ARHGAP27
10ARL17A
10ARL17B
10ARL4D
10ARL5C
10ASB16
10ATP5MC1
10ATP6V0A1
10ATXN7L3
10B4GALNT2
10BECN1
10C17ORF47
10C17ORF50
10C17ORF67
10C17ORF78
10C1QL1
10CA10
10CACNA1G
10CACNB1
10CALCOCO2
10CASC3
10CBX1
10CCDC43
10CCL14
10CCL15
10CCL16
10CCL18
10CCL23
10CCL3
10CCL3L1
10CCL3L3
10CCL4
10CCL4L1
10CCL4L2
10CCL5
10CCR10
10CCR7
10CD300LG
10CDC27
10CDK12
10CDK5RAP3
10CFAP97D1
10CISD3
10CNTD1
10CNTNAP1
10COASY
10COG1
Mod
10COPZ2
10CRHR1
10CSF3
10CUEDC1
10CWC25
10DBF4B
10DCAKD
10DDX52
10DHRS11
10DHX58
10DHX8
10DLX3
10DLX4
10DUSP14
10DUSP3
10DYNLL2
10DYNLL2-DT
10EFCAB13
10EIF1
10EME1
10EPN3
10ERBB2
10ETV4
10EZH1
10FAM117A
10FAM171A2
10FBXL20
10FBXO47
10FKBP10
10FMNL1
10FNDC8
10FZD2
10GGNBP2
10GJC1
10GJD3
10GNGT2
10GPATCH8
10GRB7
10HAP1
10HDAC5
10HEATR9
10HEXIM1
10HEXIM2
10HIGD1B
10HOXB1
10HOXB13
10HOXB2
10HOXB3
10HOXB4
10HOXB5
10HOXB6
10HOXB7
10HOXB8
10HOXB9
10HSD17B1
10HSF5
10HSPB9
10IFI35
10IGF2BP1
10IGFBP4
10KAT2A
10KAT7
10KCNH4
10KCNJ2
Mod
10KIF18B
10KIF2B
10KLHL10
10KLHL11
10KPNB1
10KRT10
10KRT12
10KRT13
10KRT14
10KRT15
10KRT16
10KRT17
10KRT19
10KRT20
10KRT222
10KRT23
10KRT24
10KRT25
10KRT26
10KRT27
10KRT28
10KRT31
10KRT32
10KRT33A
10KRT33B
10KRT34
10KRT35
10KRT36
10KRT37
10KRT38
10KRT39
10KRT40
10KRT9
10KRTAP1-1
10KRTAP1-3
10KRTAP1-4
10KRTAP1-5
10KRTAP16-1
10KRTAP17-1
10KRTAP2-1
10KRTAP2-2
10KRTAP2-3
10KRTAP2-4
10KRTAP3-1
10KRTAP3-2
10KRTAP3-3
10KRTAP4-1
10KRTAP4-11
10KRTAP4-12
10KRTAP4-2
10KRTAP4-3
10KRTAP4-4
10KRTAP4-5
10KRTAP4-6
10KRTAP4-7
10KRTAP4-8
10KRTAP4-9
10KRTAP9-1
10KRTAP9-2
10KRTAP9-3
10KRTAP9-4
10KRTAP9-6
10KRTAP9-7
10KRTAP9-8
10KRTAP9-9
10LASP1
10LHX1
10LRRC37A
10LRRC37A2
10LRRC3C
10LRRC46
10LRRC59
10LYZL6
10MED24
10MEOX1
10MIEN1
10MMP28
10MPP2
10MPP3
10MRM1
10MRPL10
10MRPL27
10MRPL45
10MRPS23
10MSI2
10MSL1
10MTMR4
10MYCBPAP
10MYL4
10MYO19
10NBR1
10NBR2
10NEUROD2
10NFE2L1
10NKIRAS2
10NLE1
10NME1
10NME1-NME2
10NME2
10NMT1
10NPEPPS
10NSRP1
Mod
10NT5C3B
10NXPH3
10OR4D1
10OR4D2
10ORMDL3
10OSBPL7
10P3H4
10PDK2
10PHB1
10PHOSPHO1
10PIP4K2B
10PLCD3
10PLEKHH3
10PLXDC1
10PPP1R1B
10PPP1R9B
10PRAC1
10PRAC2
10PRR15L
10PSMB3
10PSMC3IP
10PSMD3
10PSME3
10PTGES3L
10PTGES3L-AARSD1
10RAB5C
10RAMP2
10RAPGEFL1
10RASL10B
10RDM1
10RETREG3
10RND2
10RPL19
10RPL23
10RPL27
10RPRML
10RSAD1
10RUNDC1
10RUNDC3A
10SAMD14
10SCPEP1
10SCRN2
10SEPTIN4
10SKAP1
10SLC25A39
10SLC35B1
10SLC35G3
10SLC4A1
10SLFN11
10SLFN12
10SLFN12L
10SLFN13
10SLFN5
10SNF8
10SNX11
10SOCS7
10SP2
10SP6
10SPAG9
10SPATA20
10SPATA32
10SPMAP1
10SPPL2C
10SRCIN1
10SRSF1
10STAC2
10STARD3
10STAT5A
10STXBP4
10SUPT4H1
10SYNRG
10TAC4
10TADA2A
10TBC1D3
10TBC1D3B
10TBC1D3C
10TBC1D3F
10TBC1D3H
10TBKBP1
10TBX21
10TEX14
10TMEM100
10TMEM101
10TMEM106A
10TMEM92
10TMUB2
10TNS4
10TOB1
10TOM1L1
10TOP2A
10TRIM25
10TRQ-TTG1-1
10TSPOAP1
10TTLL6
10TUBG2
10UBE2Z
10UNC45B
10UTP18
10VAT1
10VEZF1
No
10VPS25
10WFIKKN2
10WIPF2
10WNK4
10WNT3
10WNT9B
10XYLT2
10ZNF385C
10ZNF652
10ZNHIT3
10ZPBP2
9ACADVL
Def
9ACOX1
Def
9ACTG1
Def
9AIPL1
Def
9ASPA
Def
9B9D1
Def
9C1QBP
Def
9CANT1
Def
9CCDC40
Def
9CHD3
Def
9CHRNB1
Def
9COX10
Def
9CTC1
Def
9CTNS
Def
9DNAH17
Def
9DNAH9
Def
9DPH1
Def
9ELAC2
Def
9FLCN
Def
9FOXJ1
Def
9GAA
DefSF
9GALK1
Def
9GP1BA
Def
9GUCY2D
Def
9KDM6B
Def
9MPDU1
Def
9MYH10
Def
9MYH2
Def
9MYO15A
Def
9PDE6G
Def
9PFN1
Def
9PIGL
Def
9POLR2A
Def
9PRPF8
Def
9PYCR1
Def
9RHBDF2
Def
9SCO1
Def
9SERPINF2
Def
9SGSH
Def
9TBCD
Def
9TMEM94
Def
9TNFRSF13B
Def
9TTC19
Def
9UNC13D
Def
9APPBP2
9BCAS3
9C17ORF58
9CA4
9CACNG1
9CACNG4
9CACNG5
9CCDC47
9CCT6B
9CEP112
9CEP95
9CHCT1
9CSH1
9CSH2
9CSHL1
9CYB561
9DCAF7
9DDX42
9DDX5
9DHX40
9EFCAB3
9ERN1
9FTSJ3
9GDPD1
9GH1
9GH2
9GNA13
9HEATR6
9ICAM2
9INTS2
9KCNH6
9KPNA2
9LIMD2
9LRRC37A3
9MAP3K3
9MARCHF10
9METTL2A
9MILR1
9MRC2
9NACA2
9NOL11
9PECAM1
9PITPNC1
9POLG2
9PPM1E
9PRKCA
9PRR11
9PRR29
9PSMC5
9PTRH2
9RNFT1
9SKA2
9SMARCD2
9SMURF2
9STRADA
9TBX2
9TEX2
9TUBD1
9USP32
9VMP1
9YPEL2
9ZNF830
9TMEM132E
Lim
9TMEM98
Lim
8USP22

ubiquitin specific peptidase 22

8TK1

thymidine kinase 1

8ARHGDIA
Mod
8EXOC7
Mod
8FLII
Mod
8NDUFAF8
Mod
8PAFAH1B1
8SEPTIN9
Mod
8SLC52A1
Mod
8WRAP53
Mod
8ABCA10
8ABCA5
8ABCA6
8ABCA8
8ABCA9
8ABHD15
8ADAP2
8ALDOC
8AMZ2
8ANKRD13B
8ASIC2
8ATAD5
8ATP5PD
8BLTP2
8BTBD17
8C17ORF113
8C17ORF75
8CCDC200
8CCL1
8CCL11
8CCL13
8CCL2
8CCL7
8CCL8
8CD300A
8CD300C
8CD300E
8CD300LB
8CD300LD
8CD300LF
8CDC42EP4
8CDK5R1
8CDR2L
8COPRS
8CORO6
8CPSF4L
8CRLF3
8CRYBA1
8DHRS13
8EFCAB5
8ERAL1
8EVI2A
8EVI2B
8FADS6
8FAM187A
8FAM20A
8FAM215A
8FAM222B
8FLOT2
8FMNL1-DT
8GIT1
8GOSR1
8GPR142
8GPRC5C
8GRIN2C
8HID1
8IFT20
8KCTD2
8KIF19
8KRTAP29-1
8KRTAP4-16
8KSR1
8LGALS9
8LRRC37B
8LYRM9
8MAP2K6
8MRPL58
8MTNAP1
8MTRNR2L1
8MYO18A
8MYO1D
8NAT9
8NHERF1
8NOS2
8NUFIP2
8OTOP2
8OTOP3
8PIPOX
8POLDIP2
8PROCA1
8PSMD11
8RAB11FIP4
8RAB34
8RAB37
8RHBDL3
8RHOT1
8RNF135
8RNU2-1
8RPL23A
8RPL38
8SARM1
8SDF2
8SDK2
8SEBOX
8SEZ6
8SLC13A2
8SLC16A6
8SLC38A12
8SLC39A11
8SLC46A1
8SLC6A4
Dis
8SPACA3
8SSH2
8SSTR2
8SUPT6H
8SUZ12
8TBC1D29P
8TLCD1
8TMEM132E-DT
8TMEM97
8TMIGD1
8TNFAIP1
8TP53I13
8TRAF4
8TTYH2
8UNC119
8UTP6
8VCF1
8VMA12
8WIPI1
8WSB1
8ZNF207

Possible

457 genes — click to expand
7ATPAF2
Lim
7GRAP
Lim
7MIEF2
Lim
7MRPS7
Lim
7NPTX1
Lim
7RPA1
Lim
7SLC25A10
Lim
7SLC25A19
Lim
7TIMM22
Lim
7TNFSF12
Lim
7TNFSF13
Lim
7WBP2
Lim
6CDKN2A
Def

cyclin dependent kinase inhibitor 2A

6CDH1
Def

cadherin 1

6AANAT
6ACAP1
6ADORA2B
6ADPRM
6AFMID
6AKAP1-DT
6AKAP10
6ALDH3A1
6ALDH3A2
6ALKBH5
6ALOX12
6ALOX12B
6ALOX15
6ALOX15B
6ALOXE3
6ALYREF
6ANAPC11
6ANKFY1
6ANKRD40CL
6APPBP2-DT
6ARHGAP44
6ARHGEF15
6ARL16
6ARMC7
6ARRB2
6ASGR1
6ASGR2
6ASPSCR1
6ATP1B2
6ATP2A3
6AURKB
6BACC1
6BAHCC1
6BAIAP2
6BCL6B
6BHLHA9
6BIRC5
6BORCS6
6C17ORF100
6C17ORF107
6C17ORF99
6C1QTNF1
6CAMKK1
6CAMTA2
6CARD14
6CASKIN2
6CBX2
6CBX4
6CBX8
6CCDC137
6CCDC144A
6CCDC182
6CCDC42
6CCDC57
6CD68
6CD7
6CDK3
6CDRT15
6CDRT15L2
6CDRT4
6CENPV
6CENPX
6CEP131
6CFAP52
6CHMP6
6CHRNE
6CLDN7
6CLEC10A
6CNTROB
6COPS3
6CSNK1D
6CTDNEP1
6CXCL16
6CYB5D1
6CYB5D2
6CYBC1
6CYTH1
6DERL2
6DHRS7B
6DHRS7C
6DHX33
6DNAH2
6DOC2B
6DRC3
6DRG2
6DUS1L
6DVL2
6EFCAB13-DT
6EFNB3
6EIF4A1
6EIF4A3
6EIF5A
6ELP5
6EMC6
6ENDOV
6ENGASE
6ENO3
6ENPP7
6EPN2
6EVPLL
6FAAP100
6FAM215B
6FAM83G
6FBF1
6FBXO39
6FBXW10
6FBXW10B
6FGF11
6FLJ40194
6FLJ45513
6FN3K
6FN3KRP
6FOXK2
6FSCN2
6FXR2
6GABARAP
6GALR2
6GAS7
6GEMIN4
6GGA3
6GGT6
6GH-LCR
6GID4
6GLOD4
6GLP2R
6GLTPD2
6GOSR2-DT
6GPS1
6GPS2
6GRAPL
6GRB2
6H3-3B
6HASPIN
6HEATR6-DT
6HES7
6HEXD-IT1
6HIC1
6HOXBLINC
6HS3ST3A1
6HS3ST3B1
6IGBP1C
6INCA1
6INPP5K
6ITGAE
6ITGB4
6JMJD6
6JPT1
6KCNAB3
6KCNJ12
6KCTD11
6KIAA0753
6KIF1C
6KPNB1-DT
6KRABD2
6LASP1NB
6LGALS3BP
6LGALS9B
6LGALS9C
6LHX1-DT
6LIAT1
6LLGL1
6LLGL2
6LRRC45
6LRRC75A
6MAP2K3
6MAP2K4
6MAPK7
6MAPT-IT1
6MARCHF10-DT
6MCRIP1
6MED11
6MED31
6MED9
6METRNL
6METTL16
6METTL23
6MFAP4
6MFSD11
6MFSD6L
6MGAT5B
6MIF4GD
6MINK1
6MIS12
6MPRIP
6MRM3
6MRPL12
6MRPL38
6MXRA7
6MYADML2
6MYBBP1A
6MYH1
6MYH13
6MYH3
6MYH4
6MYH8
6MYO1C
Dis
6MYOCD
6NAA38
6NATD1
6NCBP3
6NCOR1
6NDEL1
6NEURL4
6NFE2L1-DT
6NLGN2
6NLRP1
6NOTUM
6NPLOC4
6NT5C
6NT5M
6NTN1
6NUP85
6NUP88
6ODF4
6OGFOD3
6OR1A1
6OR1A2
6OR1D2
6OR1D5
6OR1E1
6OR1E2
6OR1G1
6OR3A1
6OR3A2
6OR3A3
6OVCA2
6OXLD1
6P2RX1
6P2RX5
6P4HB
6PCYT2
6PELP1
6PER1
6PGS1
6PHF23
6PICART1
6PIK3R5
Dis
6PIK3R6
6PIMREG
6PITPNA
6PITPNM3
6PLD2
6PLD6
6PLSCR3
6PPP1R27
6PRPSAP1
6PRPSAP2
6PSMB6
6QRICH2
6QTGAL
6RAB40B
6RABEP1
6RAC3
6RANGRF
Ref
6RAP1GAP2
6RASD1
6RBFOX3
Dis
6RCVRN
6RECQL5
6RFLNB
6RNASEK
6RNF112
6RNF157
6RNF167
6RNF213
6RNF222
6RNFT1-DT
6RPAIN
6RPH3AL
6RPL26
6RPTOR
6RTN4RL1
6SAP30BP
6SAT2
6SCARF1
6SCARNA20
6SCIMP
6SEC14L1
6SECTM1
6SENP3
6SERPINF1
6SGSM2
6SHISA6
6SHMT1
6SIRT7
6SLC13A5
6SLC16A11
6SLC16A13
6SLC16A3
6SLC16A5
6SLC25A11
6SLC25A35
6SLC26A11
6SLC2A4
6SLC35G6
6SLC38A10
6SLC43A2
6SLC47A1
6SLC47A2
6SLC5A10
6SMCR8
6SMG6
6SMIM36
6SMIM5
6SMTNL2
6SMYD4
6SNHG25
6SNORA21
6SNORA21B
6SNORA38B
6SNORA50C
6SNORA90
6SOCS3
6SOX15
6SP2-DT
6SPAG7
6SPATA22
6SPDYE4
6SPECC1
6SPEM1
6SPEM2
6SPHK1
6SPNS2
6SPNS3
6SREBF1
6SRP68
6SRSF2
6ST6GALNAC1
6ST6GALNAC2
6STX8
6SUMO2
6SYNGR2
6TAX1BP3
6TBC1D16
6TBC1D26
6TBC1D28
6TBC1D3D
6TBC1D3E
6TBC1D3K
6TBC1D3L
6TEKT1
Dis
6TEKT3
6TEN1
6TEPSIN
6TEX19
6TILAM
6TIMP2
6TLCD2
6TLCD3A
6TM4SF5
6TMC6
6TMC8
6TMEM102
6TMEM105
6TMEM107
6TMEM11
6TMEM220
6TMEM235
6TMEM256
6TMEM88
6TMEM95
6TNFSF12-TNFSF13
6TNK1
6TNRC6C
6TOM1L2
6TOP3A
6TRAPPC1
6TRARG1
6TRC-GCA14-1
6TRC-GCA2-2
6TRC-GCA2-3
6TRC-GCA2-4
6TRC-GCA4-1
6TRG-GCC2-6
6TRIM16
6TRIM16L
6TRIM47
6TRIM65
6TRK-TTT3-5
6TRL-TAG1-1
6TRN-GTT2-5
6TRPV1
6TRPV2
6TRPV3
6TRQ-CTG1-5
6TRR-CCG2-1
6TRR-TCT2-1
6TRSUP-TTA1-1
6TSEN54
6TSPAN10
6TSR1
6TVP23B
6TVP23C
6TVP23C-CDRT4
6TXNDC17
6UBALD2
6UBE2G1
6UBE2O
6ULK2
6USP36
6USP43
6USP6
6UTS2R
6VAMP2
6VMO1
6VPS53
6WDR45B
6WDR81
6WSCD1
6XAF1
6YBX2
6YWHAE
6ZBTB4
6ZFP3
6ZMYND15
6ZNF18
6ZNF232
6ZNF286A
6ZNF287
6ZNF594
6ZNF624
6ZNF750
6ZSWIM7
6ZZEF1
6TWIST1
Def

twist family bHLH transcription factor 1

6CLPTM1L

CLPTM1 like

5PAX8

paired box 8

5ALB
Def

albumin

4APC
DefSF

APC regulator of Wnt signaling pathway

4BRAF
Def

B-Raf proto-oncogene, serine/threonine kinase

4EGFR
Def

epidermal growth factor receptor

4SERPINC1
Def

serpin family C member 1

4NOTCH1
Def

notch receptor 1

4CASC17
4CD300H
4MGC16275
4PRO1804
4REVSEX
4SOX9CRE1
4TRR-CCT1-1
4TRR-CCT2-1
4TRR-TCG3-1
4FOXP3
Def

forkhead box P3

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Data aggregated from HPO/Monarch, ClinVar, OMIM (phenotypes + clinical synopsis), Open Targets, PanelApp, Phen2Gene, and Gene2Phenotype. Click a gene to view full details.