TRIM16L

Chr 17

tripartite motif containing 16 like (pseudogene)

Also known as: TRIM70

Predicted to be located in cytoplasm. [provided by Alliance of Genome Resources, Jul 2025]

ResearchGenerating clinical summary…
0
Active trials
0
Pubs (1 yr)
P/LP submissions
P/LP missense
1.26
LOEUF
Multiple*
Mechanism· predicted
Some data sources returned errors (1)

omim: Error: OMIM fetch failed: 429

Population Genetics & Constraint

gnomAD v4 — loss-of-function & missense intolerance

Tolerant — LoF & missense variants common in population
LoF Constraint?
1.26LOEUF
pLI 0.000
Z-score 0.87
OE 0.75 (0.461.26)
Tolerant

Highly tolerant — LoF variants common in population

Missense Constraint?
-0.14Z-score
OE missense 1.03 (0.921.15)
208 obs / 202.4 exp
Tolerant

Tolerant to missense variation

Observed / Expected Ratios?
LoF OE?0.75 (0.461.26)
00.351.4
Missense OE?1.03 (0.921.15)
00.61.4
Synonymous OE?1.12
01.21.6
LoF obs/exp: 10 / 13.4Missense obs/exp: 208 / 202.4Syn Z: -0.84

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

TRIM16L · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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