CASC17
Chr 17cancer susceptibility 17
Also known as: LINC00600
Clinical Summary— CASC17
📋
ClinVar Variants
5 Pathogenic / Likely Pathogenic· 1 VUS of 7 total submissions
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
7 submitted variants in ClinVar
Classification Summary
Pathogenic5
VUS1
Likely Benign1
5
Pathogenic
1
VUS
1
Likely Benign
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 5 |
Likely Pathogenic | — | — | — | — | 0 |
VUS | — | — | — | — | 1 |
Likely Benign | — | — | — | — | 1 |
Benign | — | — | — | — | 0 |
| Total | — | 7 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
CASC17 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →Clinical Literature
Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
Genomic Association Study for Cognitive Impairment in Parkinson's Disease
Park KW et al.·Front Neurol
2021
Genetic Variants and Haplotype Structures in the CASC Gene Family to Predict Cancer Risk: A Bioinformatics Study
Gholami M et al.·Health Sci Rep
2024
Germline genetic variants associated with somatic TMPRSS2:ERG fusion status in prostate cancer: a genome-wide association study
Ma C et al.·Cancer Epidemiol Biomarkers Prev
2023
Effect of genetic variants in UBE2O and TPK1 on facial morphology of Koreans
Cho HW et al.·Forensic Sci Res
2023
Novel prostate cancer susceptibility gene SP6 predisposes patients to aggressive disease
Sipeky C et al.·Prostate Cancer Prostatic Dis
2021Cohort
Top 5 full-text resultsSearch PubTator3 ↗
Key Publications
Landmark & review papers · by relevance
[Genetic polymorphisms of HNF1B, CASC17, CASC8 AND CCAT2 genes associated with prostate cancer risk in urologic patients].
Polukonova N V et al.·Urologiia
2025Cohort
Top 1 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
No open access results found
Top 5 resultsSearch Europe PMC ↗
External Resources
Links to major genomics databases and tools