FAM215B

Chr 17

family with sequence similarity 215 member B

Also known as: ARL17A-IT1

NCBI Gene: 644297ENSG00000232300
0
Active trials
4
Pathogenic / LP
31
ClinVar variants
1
Pubs (1 yr)
—
Missense Z
—
LOEUF
Clinical Summary— FAM215B
📋
ClinVar Variants
4 Pathogenic / Likely Pathogenic· 1 VUS of 31 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

31 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic4
VUS1
Likely Benign10
Benign16
4
Pathogenic
1
VUS
10
Likely Benign
16
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————4
Likely Pathogenic
————0
VUS
————1
Likely Benign
————10
Benign
————16
Total—31

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

FAM215B · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Landmark / reviewRecent case evidence
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
PubTator3
Top 5 full-text resultsSearch PubTator3 ↗
Key Publications
Landmark & review papers · by relevance
PubMed
Regulatory Role of miRNAs and lncRNAs in Gout.
Shu J et al.·Comput Math Methods Med
2022
Top 1 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Top 5 resultsSearch Europe PMC ↗

External Resources

Links to major genomics databases and tools

Franklin by Genoox
AI-powered variant curation and clinical analysis
DECIPHER
Genomic variants and phenotypes in rare disease patients