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TRK-TTT3-5

Chr 17

tRNA-Lys (anticodon TTT) 3-5

Also known as: TRK-TTT3-4, TRK1, TRNAK1

NCBI Gene: 7206

I don't have any information provided about the TRK-TTT3-5 gene, including its protein function, associated diseases, or inheritance pattern. Without this essential data, I cannot write a clinical summary following the strict rules to only use provided information.

Research

ResearchGenerating clinical summary…

Clinical Summary— TRK-TTT3-5

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ClinVar Variants

1 unique Pathogenic / Likely Pathogenic of 2 total submissions

Explore recent and relevant literature in Research Assistant →

Some data sources returned errors (3)

ensembl: Error: Ensembl fetch failed: 400 for /lookup/symbol/homo_sapiens/TRK-TTT3-5?content-type=application/json&expand=1

gnomad: Error: Gene not found

omim: Error: OMIM fetch failed: 429

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

2 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic1

Likely Benign1

Pathogenic

Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

Classification	Non-coding	Total
Pathogenic	1	1
Likely Pathogenic	0	0
VUS	0	0
Likely Benign	1	1
Benign	0	0
Total	2	2

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

21 pathogenic / likely-pathogenic (of 37) ClinVar copy-number / structural variants overlap TRK-TTT3-5 — these span large chromosomal regions, not the gene specifically, and are excluded from the counts above. Explore in CNV tools →