TRK-TTT3-5

Chr 17

tRNA-Lys (anticodon TTT) 3-5

Also known as: TRK-TTT3-4, TRK1, TRNAK1

37
ClinVar variants
22
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryTRK-TTT3-5
📋
ClinVar Variants
22 Pathogenic / Likely Pathogenic· 15 VUS of 37 total submissions
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/TRK-TTT3-5?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

37 submitted variants in ClinVar

Classification Summary

Pathogenic22
VUS15
22
Pathogenic
15
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
22
Likely Pathogenic
0
VUS
15
Likely Benign
0
Benign
0
Total37

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TRK-TTT3-5 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype Relationships

1 OMIM entry