Genes associated with “SPACA3”

1058 genes foundOpen Targets: X-24306 measurement7 ClinVar P/LP variants
How are genes scored? (0–100 composite)
-5–15
ClinGen
0–15
HPO Freq
0–15
Open Targets
0–12
Phen2Gene
0–10
ClinVar
0–8
Constraint
0–8
Dosage
0–8
OMIM CS
0–8
PanelApp
0–5
OMIM
0–5
G2P
0–4
Breadth
Tiers:Strong Candidates (≥20)Consider (≥8)Possible (≥3)
Evidence dots:
HPOClinVarPhen2GeneOpen TargetsPanelApp
hover for details

Strong Candidates

1 gene
1
22
score
ClinGen: DefinitiveGTR ↑
Frequency
-
P/LP Variants
5
OT Score
-

Consider

299 genes
18ASIC2

acid sensing ion channel subunit 2

18SPACA3

sperm acrosome associated 3

14RAD51D
Def
14TAOK1
Def
14CDK5R1
14PSMD11
14RAB11FIP4
14SUZ12
13HNF1B
Def
12FOXN1
Def
12LIG3
Def
12NEK8
Def
12PEX12
Def
12PHF12
Def
12PIGS
Def
11AXIN2
Def
11BPTF
Def
11COL1A1
Def
11DLG4
Def
11EFTUD2
Def
11KANSL1
Def
11NOG
Def
11PMP22
Def
11RAD51C
Def
11RAI1
Def
11SOX9
Def
11TBX4
Def
11TP53
DefSF
11GAS2L2
Mod
11NSRP1
Mod
11SLFN14
Mod
11GPR179
Def
11PGAP3
Def
11TCAP
Def
11TMEM98
Lim
10PIGW
Lim
10TAF15
Lim
10TMEM132E
Lim
10C17ORF75
10COPRS
10EVI2A
10EVI2B
10IKZF3
Mod
10LRRC37B
10MYO1D
10PCGF2
Str
10RHBDL3
10RHOT1
10UTP6
10ZNF207
9ACADVL
Def
9ACE
Def
9ACOX1
Def
9ACTG1
Def
9AIPL1
Def
9ASPA
Def
9B9D1
Def
9BRCA1
DefSF
9BRIP1
Def
9C1QBP
Def
9CANT1
Def
9CAVIN1
Def
9CCDC40
Def
9CD79B
Def
9CHD3
Def
9CHRNB1
Def
9COX10
Def
9CTC1
Def
9CTNS
Def
9DGKE
Def
9DNAAF19
Def
9DNAH17
Def
9DNAH9
Def
9DNAI2
Def
9DPH1
Def
9ELAC2
Def
9FDXR
Def
9FLCN
Def
9FOXJ1
Def
9G6PC1
Def
9G6PC3
Def
9GAA
DefSF
9GALK1
Def
9GFAP
Def
9GOSR2
Def
9GP1BA
Def
9GRN
Def
9GUCY2D
Def
9ITGA2B
Def
9ITGA3
Def
9ITGB3
Def
9KCNJ16
Def
9KDM6B
Def
9MED13
Def
9MKS1
Def
9MPDU1
Def
9MYH10
Def
9MYH2
Def
9MYO15A
Def
9NAGLU
Def
9NAGS
Def
9ODAD4
Def
9PDE6G
Def
9PFN1
Def
9PIGL
Def
9PNPO
Def
9POLR2A
Def
9PPM1D
Def
9PRKAR1A
Def
9PRPF8
Def
9PSMD12
Def
9PYCR1
Def
9RHBDF2
Def
9RNF43
Def
9SCN4A
Def
9SCO1
Def
9SERPINF2
Def
9SGCA
Def
9SGSH
Def
9SMARCE1
Def
9SMG8
Def
9SPOP
Def
9STAT3
Def
9STAT5B
Def
9TACO1
Def
9TANC2
Def
9TBCD
Def
9TLK2
Def
9TMEM94
Def
9TNFRSF13B
Def
9TRIM37
Def
9TTC19
Def
9TUBG1
Def
9UBTF
Def
9UNC13D
Def
9USH1G
Def
9ABHD15
9ACACA
9ADAP2
9ALDOC
9ANKRD13B
9AP2B1
9ATAD5
9BLTP2
9C17ORF50
9C17ORF78
9CCL1
9CCL11
9CCL13
9CCL14
9CCL15
9CCL16
9CCL18
9CCL2
9CCL23
9CCL3
9CCL3L1
9CCL3L3
9CCL4
9CCL4L1
9CCL4L2
9CCL5
9CCL7
9CCL8
9CCT6B
9CORO6
9CRLF3
9CRYBA1
9DHRS11
9DHRS13
9EFCAB5
9ERAL1
9FAM222B
9FLOT2
9FNDC8
9GGNBP2
9GIT1
9GOSR1
9HEATR9
9IFT20
9KSR1
9LGALS9
9LHX1
9LYRM9
9LYZL6
9MMP28
9MRM1
9MYO18A
9MYO19
9NLE1
9NOS2
9NUFIP2
9PIPOX
9POLDIP2
9PROCA1
9RAB34
9RASL10B
9RDM1
9RNF135
9RPL23A
9SARM1
9SDF2
9SEBOX
9SEZ6
9SLC13A2
9SLC35G3
9SLC46A1
9SLC6A4
Dis
9SLFN11
9SLFN12
9SLFN12L
9SLFN13
9SLFN5
9SPAG5
9SSH2
9SUPT6H
9TADA2A
9TBC1D29P
9TBC1D3B
9TBC1D3C
9TBC1D3H
9TLCD1
9TMEM132E-DT
9TMEM97
9TMIGD1
9TNFAIP1
9TP53I13
9TRAF4
9UNC119
9UNC45B
9VMA12
9WSB1
9ZNF830
9ZNHIT3
9CDC6
Lim
8ARHGDIA
Mod
8COG1
Mod
8EXOC7
Mod
8FLII
Mod
8KCNJ2
Mod
8MAP3K14
Mod
8NDUFAF8
Mod
8PAFAH1B1
8PLEKHM1
Mod
8RGS9
Mod
8SEPTIN9
Mod
8SLC52A1
Mod
8WRAP53
Mod
8ARHGAP23
8ARL5C
8CACNB1
8CASC3
8CCR7
8CDK12
8CISD3
8CSF3
8CWC25
8DDX52
8DUSP14
8ERBB2
8FBXL20
8FBXO47
8GJD3
8GRB7
8GSDMA
8GSDMB
8IGFBP4
8LASP1
8LRRC3C
8MED1
8MED24
8MIEN1
8MLLT6
8MRPL45
8MSL1
8MTRNR2L1
8NEUROD2
8NR1D1
8ORMDL3
8PIP4K2B
8PLXDC1
8PPP1R1B
8PSMB3
8PSMD3
8RAPGEFL1
8RPL19
8RPL23
8SOCS7
8SPMAP1
8SRCIN1
8STAC2
8STARD3
8SYNRG
8TBC1D3
8TBC1D3F
8TNS4
8TOP2A
8WIPF2
8ZPBP2

Possible

757 genes — click to expand
7ATPAF2
Lim
7COA3
Lim
7COX11
Lim
7DNAJC7
Lim
7GRAP
Lim
7MIEF2
Lim
7MRPS7
Lim
7NPTX1
Lim
7RPA1
Lim
7RPS6KB1
Lim
7SLC25A10
Lim
7SLC25A19
Lim
7TIMM22
Lim
7TNFSF12
Lim
7TNFSF13
Lim
7WBP2
Lim
6AANAT
6AARSD1
6ABCA10
6ABCA5
6ABCA6
6ABCA8
6ABCA9
6ABCC3
6ABI3
6ACAP1
6ACBD4
6ACSF2
6ADAM11
6ADORA2B
6ADPRM
6AFMID
6AKAP1
6AKAP10
6ALDH3A1
6ALDH3A2
6ALKBH5
6ALOX12
6ALOX12B
6ALOX15
6ALOX15B
6ALOXE3
6ALYREF
6AMZ2
6ANAPC11
6ANKFN1
6ANKFY1
6ANKRD40
6AOC2
6AOC3
6APPBP2
6ARHGAP27
6ARHGAP44
6ARHGEF15
6ARL16
6ARL17A
6ARL17B
6ARL4D
6ARMC7
6ARRB2
6ASB16
6ASGR1
6ASGR2
6ASPSCR1
6ATP1B2
6ATP2A3
6ATP5MC1
6ATP5PD
6ATP6V0A1
6ATXN7L3
6AURKB
6B4GALNT2
6BACC1
6BAHCC1
6BAIAP2
6BCAS3
6BCL6B
6BECN1
6BHLHA9
6BIRC5
6BORCS6
6BTBD17
6C17ORF100
6C17ORF107
6C17ORF47
6C17ORF58
6C17ORF67
6C17ORF99
6C1QL1
6C1QTNF1
6CA10
6CA4
6CACNA1G
6CACNG1
6CACNG4
6CACNG5
6CALCOCO2
6CAMKK1
6CAMTA2
6CARD14
6CASKIN2
6CBX1
6CBX2
6CBX4
6CBX8
6CCDC137
6CCDC144A
6CCDC42
6CCDC43
6CCDC47
6CCDC57
6CCR10
6CD300A
6CD300C
6CD300E
6CD300LB
6CD300LD
6CD300LF
6CD300LG
6CD68
6CD7
6CDC27
6CDC42EP4
6CDK3
6CDK5RAP3
6CDR2L
6CDRT15
6CDRT15L2
6CDRT4
6CENPV
6CENPX
6CEP112
6CEP131
6CEP95
6CFAP52
6CFAP97D1
6CHCT1
6CHMP6
6CHRNE
6CLDN7
6CLEC10A
6CNTD1
6CNTNAP1
6CNTROB
6COASY
6COPS3
6COPZ2
6CPSF4L
6CRHR1
6CSH1
6CSH2
6CSHL1
6CSNK1D
6CTDNEP1
6CUEDC1
6CXCL16
6CYB561
6CYB5D1
6CYB5D2
6CYBC1
6CYTH1
6DBF4B
6DCAF7
6DCAKD
6DDX42
6DDX5
6DERL2
6DHRS7B
6DHRS7C
6DHX33
6DHX40
6DHX58
6DHX8
6DLX3
6DLX4
6DNAH2
6DOC2B
6DRC3
6DRG2
6DUS1L
6DUSP3
6DVL2
6DYNLL2
6DYNLL2-DT
6EFCAB13
6EFCAB3
6EFNB3
6EIF1
6EIF4A1
6EIF4A3
6EIF5A
6ELP5
6EMC6
6EME1
6ENDOV
6ENGASE
6ENO3
6ENPP7
6EPN2
6EPN3
6ERN1
6ETV4
6EVPLL
6EZH1
6FAAP100
6FADS6
6FAM117A
6FAM171A2
6FAM20A
6FAM83G
6FBF1
6FBXO39
6FBXW10
6FBXW10B
6FGF11
6FKBP10
6FMNL1
6FN3K
6FN3KRP
6FOXK2
6FSCN2
6FTSJ3
6FXR2
6FZD2
6GABARAP
6GALR2
6GAS7
6GDPD1
6GEMIN4
6GGA3
6GGT6
6GH1
6GH2
6GID4
6GJC1
6GLOD4
6GLP2R
6GLTPD2
6GNA13
6GNGT2
6GPATCH8
6GPR142
6GPRC5C
6GPS1
6GPS2
6GRAPL
6GRB2
6GRIN2C
6H3-3B
6HAP1
6HASPIN
6HDAC5
6HEATR6
6HES7
6HEXD-IT1
6HEXIM1
6HEXIM2
6HIC1
6HID1
6HIGD1B
6HOXB1
6HOXB13
6HOXB2
6HOXB3
6HOXB4
6HOXB5
6HOXB6
6HOXB7
6HOXB8
6HOXB9
6HS3ST3A1
6HS3ST3B1
6HSD17B1
6HSF5
6HSPB9
6ICAM2
6IFI35
6IGF2BP1
6INCA1
6INPP5K
6INTS2
6ITGAE
6ITGB4
6JMJD6
6JPT1
6KAT2A
6KAT7
6KCNAB3
6KCNH4
6KCNH6
6KCNJ12
6KCTD11
6KCTD2
6KIAA0753
6KIF18B
6KIF19
6KIF1C
6KIF2B
6KLHL10
6KLHL11
6KPNA2
6KPNB1
6KRABD2
6KRT10
6KRT12
6KRT13
6KRT14
6KRT15
6KRT16
6KRT17
6KRT19
6KRT20
6KRT222
6KRT23
6KRT24
6KRT25
6KRT26
6KRT27
6KRT28
6KRT31
6KRT32
6KRT33A
6KRT33B
6KRT34
6KRT35
6KRT36
6KRT37
6KRT38
6KRT39
6KRT40
6KRT9
6KRTAP1-1
6KRTAP1-3
6KRTAP1-4
6KRTAP1-5
6KRTAP16-1
6KRTAP17-1
6KRTAP2-1
6KRTAP2-2
6KRTAP2-3
6KRTAP2-4
6KRTAP3-1
6KRTAP3-2
6KRTAP3-3
6KRTAP4-1
6KRTAP4-11
6KRTAP4-12
6KRTAP4-2
6KRTAP4-3
6KRTAP4-4
6KRTAP4-5
6KRTAP4-6
6KRTAP4-7
6KRTAP4-8
6KRTAP4-9
6KRTAP9-1
6KRTAP9-2
6KRTAP9-3
6KRTAP9-4
6KRTAP9-6
6KRTAP9-7
6KRTAP9-8
6KRTAP9-9
6LGALS3BP
6LGALS9B
6LGALS9C
6LIAT1
6LIMD2
6LLGL1
6LLGL2
6LRRC37A
6LRRC37A2
6LRRC37A3
6LRRC45
6LRRC46
6LRRC59
6LRRC75A
6LSM12
6LUC7L3
6MAP2K3
6MAP2K4
6MAP2K6
6MAP3K3
6MAPK7
6MARCHF10
6MBTD1
6MCRIP1
6MED11
6MED31
6MED9
6MEIOC
6MEOX1
6METRNL
6METTL16
6METTL23
6METTL2A
6MFAP4
6MFSD11
6MFSD6L
6MGAT5B
6MIF4GD
6MILR1
6MINK1
6MIS12
6MPP2
6MPP3
6MPRIP
6MRC2
6MRM3
6MRPL10
6MRPL12
6MRPL27
6MRPL38
6MRPL58
6MRPS23
6MSI2
6MTMR4
6MTNAP1
6MXRA7
6MYADML2
6MYBBP1A
6MYCBPAP
6MYH1
6MYH13
6MYH3
6MYH4
6MYH8
6MYL4
6MYO1C
Dis
6MYOCD
6NAA38
6NACA2
6NAT9
6NATD1
6NBR1
6NBR2
6NCBP3
6NCOR1
6NDEL1
6NEURL4
6NFE2L1
6NHERF1
6NKIRAS2
6NLGN2
6NLRP1
6NME1
6NME1-NME2
6NME2
6NMT1
6NOL11
6NOTUM
6NPEPPS
6NPLOC4
6NT5C
6NT5C3B
6NT5M
6NTN1
6NUP85
6NUP88
6NXPH3
6ODF4
6OGFOD3
6OR1A1
6OR1A2
6OR1D2
6OR1D5
6OR1E1
6OR1E2
6OR1G1
6OR3A1
6OR3A2
6OR3A3
6OR4D1
6OR4D2
6OSBPL7
6OTOP2
6OTOP3
6OVCA2
6OXLD1
6P2RX1
6P2RX5
6P3H4
6P4HB
6PCYT2
6PDK2
6PECAM1
6PELP1
6PER1
6PGS1
6PHB1
6PHF23
6PHOSPHO1
6PIK3R5
Dis
6PIK3R6
6PIMREG
6PITPNA
6PITPNC1
6PITPNM3
6PLCD3
6PLD2
6PLD6
6PLEKHH3
6PLSCR3
6POLG2
6PPM1E
6PPP1R27
6PPP1R9B
6PRAC1
6PRAC2
6PRKCA
6PRPSAP1
6PRPSAP2
6PRR11
6PRR15L
6PRR29
6PSMB6
6PSMC3IP
6PSMC5
6PSME3
6PTGES3L
6PTGES3L-AARSD1
6PTRH2
6QRICH2
6QTGAL
6RAB37
6RAB40B
6RAB5C
6RABEP1
6RAC3
6RAMP2
6RANGRF
Ref
6RAP1GAP2
6RASD1
6RBFOX3
Dis
6RCVRN
6RECQL5
6RETREG3
6RFLNB
6RNASEK
6RND2
6RNF112
6RNF157
6RNF167
6RNF213
6RNF222
6RNFT1
6RPAIN
6RPH3AL
6RPL26
6RPL27
6RPL38
6RPRML
6RPTOR
6RSAD1
6RTN4RL1
6RUNDC1
6RUNDC3A
6SAMD14
6SAP30BP
6SAT2
6SCARF1
6SCIMP
6SCPEP1
6SCRN2
6SDK2
6SEC14L1
6SECTM1
6SENP3
6SEPTIN4
6SERPINF1
6SGSM2
6SHISA6
6SHMT1
6SIRT7
6SKA2
6SKAP1
6SLC13A5
6SLC16A11
6SLC16A13
6SLC16A3
6SLC16A5
6SLC16A6
6SLC25A11
6SLC25A35
6SLC25A39
6SLC26A11
6SLC2A4
6SLC35B1
6SLC35G6
6SLC38A10
6SLC38A12
6SLC39A11
6SLC43A2
6SLC47A1
6SLC47A2
6SLC4A1
6SLC5A10
6SMARCD2
6SMCR8
6SMG6
6SMIM5
6SMTNL2
6SMURF2
6SMYD4
6SNF8
6SNX11
6SOCS3
6SOX15
6SP2
6SP6
6SPAG7
6SPAG9
6SPATA20
6SPATA22
6SPATA32
6SPDYE4
6SPECC1
6SPEM1
6SPEM2
6SPHK1
6SPNS2
6SPNS3
6SPPL2C
6SREBF1
6SRP68
6SRSF1
6SRSF2
6SSTR2
6ST6GALNAC1
6ST6GALNAC2
6STAT5A
6STRADA
6STX8
6STXBP4
6SUMO2
6SUPT4H1
6SYNGR2
6TAC4
6TAX1BP3
6TBC1D16
6TBC1D26
6TBC1D28
6TBKBP1
6TBX2
6TBX21
6TEKT1
Dis
6TEKT3
6TEN1
6TEPSIN
6TEX14
6TEX19
6TEX2
6TIMP2
6TK1
6TLCD2
6TLCD3A
6TM4SF5
6TMC6
6TMC8
6TMEM100
6TMEM101
6TMEM102
6TMEM105
6TMEM106A
6TMEM107
6TMEM11
6TMEM220
6TMEM235
6TMEM256
6TMEM88
6TMEM92
6TMEM95
6TMUB2
6TNFSF12-TNFSF13
6TNK1
6TNRC6C
6TOB1
6TOM1L1
6TOM1L2
6TOP3A
6TRAPPC1
6TRARG1
6TRG-GCC2-6
6TRIM16
6TRIM16L
6TRIM25
6TRIM47
6TRIM65
6TRK-TTT3-5
6TRL-TAG1-1
6TRPV1
6TRPV2
6TRPV3
6TRQ-CTG1-5
6TRQ-TTG1-1
6TRR-TCT2-1
6TSEN54
6TSPAN10
6TSPOAP1
6TSR1
6TTLL6
6TTYH2
6TUBD1
6TUBG2
6TVP23B
6TVP23C
6TVP23C-CDRT4
6TXNDC17
6UBALD2
6UBE2G1
6UBE2O
6UBE2Z
6ULK2
6USP22
6USP32
6USP36
6USP43
6USP6
6UTP18
6UTS2R
6VAMP2
6VAT1
6VCF1
6VEZF1
No
6VMO1
6VMP1
6VPS25
6VPS53
6WDR45B
6WDR81
6WFIKKN2
6WIPI1
6WNK4
6WNT3
6WNT9B
6WSCD1
6XAF1
6XYLT2
6YBX2
6YPEL2
6YWHAE
6ZBTB4
6ZFP3
6ZMYND15
6ZNF18
6ZNF232
6ZNF286A
6ZNF287
6ZNF385C
6ZNF594
6ZNF624
6ZNF652
6ZNF750
6ZSWIM7
6ZZEF1
4SLC35F5

solute carrier family 35 member F5

4DISC1

DISC1 scaffold protein

Related phenotype searches

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Data aggregated from HPO/Monarch, ClinVar, OMIM (phenotypes + clinical synopsis), Open Targets, PanelApp, Phen2Gene, and Gene2Phenotype. Click a gene to view full details.