Genes associated with “intellectual disability”
How are genes scored? (0–100 composite)
Strong Candidates
86 genesAT-hook DNA binding motif containing 1
Moderate intellectual disability
mediator complex subunit 13L
Intellectual disability
glutamine rich 1
Intellectual disability
solute carrier family 6 member 8
zinc finger MYND-type containing 11
Mild intellectual disability
Severe intellectual disability
CCCTC-binding factor
Intellectual disability
pogo transposable element derived with ZNF domain
DEAD-box helicase 3 X-linked
lysine methyltransferase 2C
Intellectual disability
Severe intellectual disability
Moderate intellectual disability
Intellectual disability
myelin transcription factor 1 like
purine rich element binding protein A
Intellectual disability
Mild intellectual disability
Severe intellectual disability
Intellectual disability
transcription factor 20
Intellectual disability
SET domain containing 2, histone lysine methyltransferase
Intellectual disability
Intellectual disability
Intellectual disability
tubulin alpha 1a
Intellectual disability
p53-induced death domain protein 1
BCL11 transcription factor A
Intellectual disability
Intellectual disability
Severe intellectual disability
solute carrier family 2 member 1
Profound intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
syntaxin 1A
Intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
Mild intellectual disability
SATB homeobox 2
Consider
217 geneslysine methyltransferase 2E (inactive)
KAT8 regulatory NSL complex subunit 1
neurobeachin
Intellectual disability
synaptotagmin 1
Mild intellectual disability
calcium/calmodulin dependent protein kinase II alpha
Intellectual disability
gamma-aminobutyric acid type A receptor subunit beta2
protein phosphatase 2 regulatory subunit B'delta
ARF guanine nucleotide exchange factor 1
calcium/calmodulin dependent protein kinase II beta
Moderate intellectual disability
phosphofurin acidic cluster sorting protein 1
YY1 transcription factor
Intellectual disability
polycomb group ring finger 2
potassium voltage-gated channel subfamily H member 1
SWI/SNF related BAF chromatin remodeling complex subunit C2
FERM and PDZ domain containing 4
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
potassium calcium-activated channel subfamily N member 2
ARF GTPase 3
lysine demethylase 5A
Intellectual disability
Intellectual disability
vesicle associated membrane protein 2
Intellectual disability
post-GPI attachment to proteins 2
ubiquitin specific peptidase 27 X-linked
Intellectual disability
Severe intellectual disability
DEAD-box helicase 6
Severe intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Severe intellectual disability
ARTHROGRYPOSIS, CLEFT PALATE, CRANIOSYNOSTOSIS, AND IMPAIRED INTELLECTUAL DEVELOPMENT; ACCIID
ALOPECIA-INTELLECTUAL DISABILITY SYNDROME 1; APMR1
Alopecia-intellectual disability syndrome 2
Alopecia-intellectual disability syndrome 3
ALOPECIA-INTELLECTUAL DISABILITY SYNDROME 4; APMR4
CLEFT PALATE, CARDIAC DEFECTS, AND IMPAIRED INTELLECTUAL DEVELOPMENT; CPCMR
DEVELOPMENTAL DELAY WITH VARIABLE INTELLECTUAL DISABILITY AND DYSMORPHIC FACIES; DIDDF
INTELLECTUAL DISABILITY AND MYOPATHY SYNDROME; IDMYS
INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL RECESSIVE 65; MRT65
INTELLECTUAL DISABILITY-HYPOTONIC FACIES SYNDROME, X-LINKED, 1; MRXHF1
SHORT STATURE, BRACHYDACTYLY, IMPAIRED INTELLECTUAL DEVELOPMENT, AND SEIZURES; SBIDDS
INTELLECTUAL DEVELOPMENTAL DISORDER, X-LINKED 1; XLID1
Intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
Severe intellectual disability
Mild intellectual disability
Intellectual disability
Intellectual disability
Moderate intellectual disability
Severe intellectual disability
Intellectual disability
Mild intellectual disability
Intellectual disability
Mild intellectual disability
Intellectual disability
Mild intellectual disability
Moderate intellectual disability
Severe intellectual disability
Moderate intellectual disability
Intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
Moderate intellectual disability
Mild intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Profound intellectual disability
Severe intellectual disability
Intellectual disability
Mild intellectual disability
Intellectual disability
Intellectual disability
Mild intellectual disability
Intellectual disability
Intellectual disability
Possible
94 genes — click to expand
Severe intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
Severe intellectual disability
Mild intellectual disability
Intellectual disability
Mild intellectual disability
Moderate intellectual disability
Intellectual disability
Profound intellectual disability
Intellectual disability
Intellectual disability
Moderate intellectual disability
Severe intellectual disability
Intellectual disability
Intellectual disability
Severe intellectual disability
Profound intellectual disability
Intellectual disability
Severe intellectual disability
Severe intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Severe intellectual disability
Intellectual disability
Severe intellectual disability
Mild intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
EPILEPSY, X-LINKED 1, WITH VARIABLE LEARNING DISABILITIES AND BEHAVIOR DISORDERS; EPILX1
Intellectual disability
Mild intellectual disability
Intellectual disability
Mild intellectual disability
Mild intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Mild intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Intellectual disability
Mild intellectual disability
Related phenotype searches
Data aggregated from HPO/Monarch, ClinVar, OMIM (phenotypes + clinical synopsis), Open Targets, PanelApp, Phen2Gene, and Gene2Phenotype. Click a gene to view full details.