RNVU1-7

Chr 1

RNA, variant U1 small nuclear 7

Also known as: RNU1-26P, RNU1-6, RNU1-6P, RNU1-9, RNU1-9P, RNVU1-9, vU1.7, vU1.9

NCBI Gene: 26864ENSG00000206585

Predicted to enable pre-mRNA 5'-splice site binding activity. Predicted to be involved in mRNA 5'-splice site recognition. Predicted to be part of U1 snRNP. [provided by Alliance of Genome Resources, Jul 2025]

123
ClinVar variants
121
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— RNVU1-7
📋
ClinVar Variants
121 Pathogenic / Likely Pathogenic· 2 VUS of 123 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

123 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic102
Likely Pathogenic19
VUS2
102
Pathogenic
19
Likely Pathogenic
2
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————102
Likely Pathogenic
————19
VUS
————2
Likely Benign
————0
Benign
————0
Total—123

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

RNVU1-7 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

OMIM

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence

No publications found for RNVU1-7

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools