MVP-DT

Chr 16

MVP divergent transcript

NCBI Gene: 112268170ENSG00000238045
935
ClinVar variants
78
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— MVP-DT
📋
ClinVar Variants
78 Pathogenic / Likely Pathogenic· 221 VUS of 935 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

935 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic62
Likely Pathogenic16
VUS221
Likely Benign80
Conflicting6
62
Pathogenic
16
Likely Pathogenic
221
VUS
80
Likely Benign
6
Conflicting

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
33
3
26
0
62
Likely Pathogenic
9
6
1
0
16
VUS
7
208
4
2
221
Likely Benign
0
12
5
63
80
Benign
0
0
0
0
0
Conflicting
—6
Total492293665385

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

MVP-DT · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

OMIM

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence

No publications found for MVP-DT

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools