MVP-DT
Chr 16MVP divergent transcript
I cannot provide a clinical summary for MVP-DT as no information about this gene's protein function, associated diseases, or inheritance pattern has been provided in the data below the rules. Without specific details about what the protein does, what conditions result from mutations, and how it is inherited, I cannot write an accurate clinical summary that adheres to the requirement of using only the information provided.
Some data sources returned errors (1)
omim: Error: OMIM fetch failed: 429
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
399 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | 48 | 5 | 10 | 0 | 63 |
Likely Pathogenic | 10 | 6 | 0 | 0 | 16 |
VUS | 7 | 209 | 2 | 2 | 220 |
Likely Benign | 0 | 14 | 3 | 63 | 80 |
Benign | 0 | 0 | 0 | 0 | 0 |
Conflicting | — | 6 | |||
| Total | 65 | 234 | 15 | 65 | 385 |
LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
MVP-DT · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools