SLX1A-SULT1A3
Chr 16SLX1A-SULT1A3 readthrough (NMD candidate)
This locus represents a naturally occurring read-through transcript between the SLX1A and SULT1A3 genes that is likely subject to nonsense-mediated decay and unlikely to produce a functional protein product. No disease associations have been established for this read-through transcript.
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
76 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | 0 | 0 | 32 | 0 | 32 |
Likely Pathogenic | 0 | 0 | 9 | 0 | 9 |
VUS | 0 | 30 | 1 | 0 | 31 |
Likely Benign | 0 | 2 | 0 | 2 | 4 |
Benign | 0 | 0 | 0 | 0 | 0 |
| Total | 0 | 32 | 42 | 2 | 76 |
LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
SLX1A-SULT1A3 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools