CIROZ

Chr 1AR

ciliated left-right organizer protein containing ZP-N domains

Also known as: C1orf127, HTX14

NCBI Gene: 148345ENSG00000175262UniProt: Q8N9H9OMIM: 619700

Predicted to act upstream of or within determination of left/right symmetry and heart development. [provided by Alliance of Genome Resources, Apr 2025]

OMIMResearchGenerating clinical summary…
AR1 OMIM phenotype
Clinical Summary— CIROZ
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Some data sources returned errors (1)

gnomad: Error: Gene not found

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

ClinVar

Protein Context — Lollipop Plot

CIROZ · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

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External Resources

Links to major genomics databases and tools

Franklin by Genoox
AI-powered variant curation and clinical analysis
DECIPHER
Genomic variants and phenotypes in rare disease patients