Genes associated with “seizures”
Some sources returned errors (1)
hpo: Error: Monarch API: 502
How are genes scored? (0–100 composite)
Strong Candidates
18 genesgamma-aminobutyric acid type A receptor subunit beta3
gamma-aminobutyric acid type A receptor subunit alpha1
Consider
115 genessolute carrier family 6 member 1
sodium voltage-gated channel alpha subunit 9
glutamate ionotropic receptor AMPA type subunit 4
solute carrier family 2 member 1
calcium voltage-gated channel auxiliary subunit alpha2delta 1
sodium voltage-gated channel alpha subunit 4
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
gamma-aminobutyric acid type A receptor subunit beta2
adhesion G protein-coupled receptor V1
SEIZURES, BENIGN FAMILIAL NEONATAL, 1; BFNS1
SEIZURES, BENIGN FAMILIAL NEONATAL, 2; BFNS2
DEAFNESS, ONYCHODYSTROPHY, OSTEODYSTROPHY, IMPAIRED INTELLECTUAL DEVELOPMENT, AND SEIZURES SYNDROME; DOORS
Febrile seizures, familial, 1
FEBRILE SEIZURES, FAMILIAL, 11; FEB11
Generalized epilepsy with febrile seizures plus, type 7
HYPERGLYCINEMIA, LACTIC ACIDOSIS, AND SEIZURES; HGCLAS
INTELLECTUAL DEVELOPMENTAL DISORDER, AUTOSOMAL DOMINANT 6, WITH OR WITHOUT SEIZURES; MRD6
NEURODEVELOPMENTAL DISORDER WITH OR WITHOUT HYPERKINETIC MOVEMENTS AND SEIZURES, AUTOSOMAL DOMINANT; NDHMSD
RIGIDITY AND MULTIFOCAL SEIZURE SYNDROME, LETHAL NEONATAL; RMFSL
glutamate ionotropic receptor AMPA type subunit 3
potassium voltage-gated channel subfamily Q member 3
glutamate ionotropic receptor kainate type subunit 2
tripartite motif containing 8
aldehyde dehydrogenase 5 family member A1
glutamate ionotropic receptor NMDA type subunit 2A
sodium voltage-gated channel alpha subunit 5
sodium voltage-gated channel alpha subunit 11
carbonic anhydrase 2
glutamate ionotropic receptor AMPA type subunit 2
gamma-aminobutyric acid type A receptor subunit delta
gamma-aminobutyric acid type A receptor subunit beta1
glutamate ionotropic receptor AMPA type subunit 1
gamma-aminobutyric acid type A receptor subunit alpha2
gamma-aminobutyric acid type A receptor subunit alpha5
sodium voltage-gated channel alpha subunit 7
ARF GTPase 3
synaptic vesicle glycoprotein 2A
sodium voltage-gated channel alpha subunit 10
carbonic anhydrase 4
carbonic anhydrase 1
carbonic anhydrase 12
gamma-aminobutyric acid type A receptor subunit alpha3
gamma-aminobutyric acid type A receptor subunit gamma1
gamma-aminobutyric acid type A receptor subunit gamma3
gamma-aminobutyric acid type A receptor subunit alpha6
gamma-aminobutyric acid type A receptor subunit epsilon
gamma-aminobutyric acid type A receptor subunit alpha4
gamma-aminobutyric acid type A receptor subunit pi
gamma-aminobutyric acid type A receptor subunit theta
potassium calcium-activated channel subfamily N member 2
Possible
74 genes — click to expand
EPILEPSY, IDIOPATHIC GENERALIZED, SUSCEPTIBILITY TO, 17; EIG17
GENERALIZED EPILEPSY WITH FEBRILE SEIZURES PLUS, TYPE 2; GEFSP2
HYPOMAGNESEMIA, SEIZURES, AND IMPAIRED INTELLECTUAL DEVELOPMENT 1; HOMGSMR1
MULTIPLE CONGENITAL ANOMALIES-HYPOTONIA-SEIZURES SYNDROME 1; MCAHS1
MULTIPLE CONGENITAL ANOMALIES-HYPOTONIA-SEIZURES SYNDROME 2; MCAHS2
NEURODEVELOPMENTAL DISORDER WITH HYPOTONIA AND IMPAIRED EXPRESSIVE LANGUAGE AND WITH OR WITHOUT SEIZURES; NEDHELS
OPTIC ATROPHY 10 WITH OR WITHOUT ATAXIA, IMPAIRED INTELLECTUAL DEVELOPMENT, AND SEIZURES; OPA10
Related phenotype searches
Data aggregated from HPO/Monarch, ClinVar, OMIM (phenotypes + clinical synopsis), Open Targets, PanelApp, Phen2Gene, and Gene2Phenotype. Click a gene to view full details.