CHKB-CPT1B

Chr 22

CHKB-CPT1B readthrough (NMD candidate)

Also known as: CHKL-CPT1B, CPT1-M, CPT1B, CPTI-M

CHKB-CPT1B represents read-through transcripts from adjacent genes CHKB and CPT1B on chromosome 22 that are candidates for nonsense-mediated mRNA decay and unlikely to produce functional proteins. No disease associations have been established for this read-through transcript, as pathogenic variants would be expected to affect the individual CHKB or CPT1B genes rather than the read-through product.

ResearchSummary from RefSeq

The genes CHKB and CPT1B are adjacent on chromosome 22 and read-through transcripts are expressed that include exons from both loci. The read-through transcripts are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to express proteins. [provided by RefSeq, Jun 2009]

ResearchGenerating clinical summary…

Active trials

Pubs (1 yr)

—

P/LP submissions

—

P/LP missense

—

LOEUF

—

Mechanism

Some data sources returned errors (1)