SNHG14
Chr 15small nucleolar RNA host gene 14
Also known as: 115HG, IC-SNURF-SNRPN, LNCAT, NCRNA00214, U-UBE3A-ATS, UBE3A-AS, UBE3A-AS1, UBE3A-ATS
SNHG14 produces a long non-coding RNA that hosts small nucleolar RNAs (snoRNAs) and regulates imprinted expression of UBE3A in the brain through antisense transcription. Mutations cause Prader-Willi syndrome, characterized by neonatal hypotonia, feeding difficulties in infancy followed by hyperphagia and obesity, intellectual disability, and behavioral problems. The gene follows genomic imprinting with paternal expression and is located in the Prader-Willi critical region on chromosome 15.
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
SNHG14 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
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Links to major genomics databases and tools