m.961T>G
Resolving variant against ClinVar, gnomAD and Ensembl…
Resolving variant against ClinVar, gnomAD and Ensembl…
Aminoglycosides: uncertain-risk MT-RNR1 variant (CPIC)
Weak or no evidence of increased risk: standard doses for the shortest feasible course with drug-level monitoring, and regular hearing checks. CPIC: optional recommendation · CPIC guideline, McDermott et al. 2022 (PMID 34032273)
Tap or hover a gene, landmark or tick; genes open their page, ticks their variant.
m.941–981 of the revised Cambridge Reference Sequence (NC_012920.1); the boxed base is m.961 T→G.
37 genes from Ensembl (rCRS numbering, matched to MITOMAP’s Gene Loci); landmarks and disease alleles from MITOMAP (CC BY 3.0). Circular layout after MitoWheel.