MT-TQ
Chr MTtRNA-Gln
Also known as: MTTQ
Predicted to enable triplet codon-amino acid adaptor activity. Predicted to be involved in translation. [provided by Alliance of Genome Resources, Jul 2025]
Clinical highlights
Some data sources returned errors (1)
omim: Error: OMIM fetch failed: 429
MT-TQ is a mitochondrial tRNA gene. gnomAD constraint, carrier burden and exome coverage, the ClinVar type breakdown, the protein lollipop, AlphaFold and transcript-architecture views are built for nuclear genes and are not shown. Population data for mtDNA variants (gnomAD v3.1, homoplasmy and heteroplasmy) is on each variant page.
Where it sits in the mitochondrial genome
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37 genes from Ensembl (rCRS numbering, matched to MITOMAP’s Gene Loci); landmarks and disease alleles from MITOMAP (CC BY 3.0). Circular layout after MitoWheel.
ClinVar Variant Classifications
0 submitted variants in ClinVar
MITOMAP Disease Variants — MT-TQ
Live table ↗| Variant | Disease | Status | GenBank seqs |
|---|---|---|---|
| m.4332G>A | Encephalopathy / MELAS | Uncertain significance · confirmed | 0 |
| m.4336T>C | ADPD / Hearing Loss & Migraine / autism spectrum / intellectual disability | Benign · reported | 563 |
| m.4343A>G | Poss. hypertension factor | Reported | 55 |
| m.4344T>C | Developmental delay | Reported | 0 |
| m.4345C>T | Poss. hypertension factor | Reported | 6 |
| m.4353T>C | Poss. hypertension factor | Reported | 40 |
| m.4363T>C | Metabolic syndrome and polycystic ovary syndrome / possibly associated w DEAF + RP + dev delay / hypertension / LHON | Reported | 56 |
| m.4369A>AA | Myopathy | Uncertain significance · reported | 0 |
| m.4372C>T | Suspected mito disease | Uncertain significance · reported | 0 |
| m.4373T>C | Tic disorder / possibly LVNC-associated | Reported | 11 |
| m.4375C>T | Matrilineal hypertension risk factor | Reported | 10 |
| m.4381A>G | LHON | Reported | 4 |
| m.4386T>C | Heart disease / myopathy / hypertension | Conflicting reports | 198 |
| m.4387C>A | Poss. hypertension factor | Reported | 2 |
| m.4388A>G | Poss. hypertension factor; intellectual disability | Reported | 101 |
| m.4392C>T | Poss. hypertension factor | Reported | 20 |
| m.4395A>G | Poss. hypertension factor | Reported | 36 |
As of 2026-10-07 — a dated copy; MITOMAP can’t be fetched live, and the live table may be newer.
Source: MITOMAP (mitomap.org), CC BY 3.0
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
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Links to major genomics databases and tools