MT-TA

Chr MT

tRNA-Ala

Also known as: MTTA

NCBI Gene: 4553 ENSG00000210127

GeneReviews ResearchGenerating clinical summary…

Clinical highlights

Gene-disease validity (ClinGen)

mitochondrial disease · MTDefinitivesufficient evidence for diagnostic panels

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P/LP submissions

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P/LP missense

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LOEUF

📖

GeneReview available — MT-TA

Authoritative clinical overview · Recommended first read

Open GeneReview ↗

Some data sources returned errors (1)

omim: Error: OMIM fetch failed: 429

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

MT-TA · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

External Resources

Links to major genomics databases and tools

Franklin by Genoox

AI-powered variant curation and clinical analysis

Genomic variants and phenotypes in rare disease patients

📖

GeneReview available — MT-TA

Authoritative clinical overview · NCBI Bookshelf · Recommended first read

Open GeneReview ↗

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

Infiltrating Bladder Urothelial CarcinomaStage II Bladder Urothelial CarcinomaStage III Bladder Urothelial Carcinoma

Gemcitabine and Cisplatin Without Cystectomy for Patients With Muscle Invasive Bladder Urothelial Cancer and Select Genetic Alterations

ACTIVE NOT RECRUITING

NCT03609216Phase PHASE2Alliance for Clinical Trials in OncologyStarted 2018-12-10

Gemcitabine HydrochlorideCisplatinPegfilgrastim

External Resources

Links to major genomics databases and tools

Franklin by Genoox

AI-powered variant curation and clinical analysis

Genomic variants and phenotypes in rare disease patients