MT-TT:m.15923A>G

Tutor Research

Nomenclaturem.15923A>GchrMT:15923|ClinVar #39575

Typemitochondrial tRNA variant

InheritanceMitochondrial

gnomAD mtDNA

Absent

of 56,427 genomes

MitoTIP

12.4 · Q3 possibly benign

PON-mt-tRNA

0.61 · likely pathogenic

Tutor Research

ClinVarLikely pathogenic

VCV000039575

Review: reviewed by expert panelSubmitters: 5view ↗Last evaluated: 2023/06/26 00:00

Mitochondrial disease[MedGen][Orphanet][MONDO]

MITOMAPLikely pathogenicconfirmed

Live entry

Disease: Lethal infantile mitochondrial myopathy (LIMM) · Myoclonic epilepsy with ragged-red fibres (MERRF) · Mito diseaseReported as: homoplasmic and heteroplasmicGenBank: 0 sequences

MITOMAP (mitomap.org), CC BY 3.0 · disease table as of 2026-10-07

Where it sits in the mitochondrial genome

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proteinrRNAtRNAouter ring H-strand · inner L-strandMITOMAP confirmedreported (as of 2026-10-07)

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ACTAATACACCAGTCTTGTAAACCGGAGATGAAAACCTTTT

MT-TT

m.15903–15943 of the revised Cambridge Reference Sequence (NC_012920.1); the boxed base is m.15923 A→G.

37 genes from Ensembl (rCRS numbering, matched to MITOMAP’s Gene Loci); landmarks and disease alleles from MITOMAP (CC BY 3.0). Circular layout after MitoWheel.