MT-TE:m.14687A>G

Tutor Research

Nomenclaturem.14687A>GchrMT:14687|ClinVar #690201

Typemitochondrial tRNA variant

InheritanceMitochondrial

gnomAD mtDNA

447 hom · 2 het

of 56,433 genomes

MitoTIP

3.2 · Q4 likely benign

PON-mt-tRNA

0.45 · likely neutral

Tutor Research

ClinVarBenign

VCV000690201

Review: criteria provided, single submitterSubmitters: 1view ↗Last evaluated: 2019/07/12 00:00

MELAS syndrome[OMIM][MedGen][Orphanet][MONDO]

MITOMAPReported

Live entry

Disease: Mito myopathy w respiratory failure · Intellectual disabilityReported as: homoplasmicGenBank: 396 sequences

MITOMAP (mitomap.org), CC BY 3.0 · disease table as of 2026-10-07

Where it sits in the mitochondrial genome

Tap or hover a gene, landmark or tick; genes open their page, ticks their variant.

proteinrRNAtRNAouter ring H-strand · inner L-strandMITOMAP confirmedreported (as of 2026-10-07)

||||

ACATCATTATTCTCGCACGGACTACAACCACGACCAATGAT

MT-ND6 (L-strand) · ends m.14673

MT-TE (L-strand) · starts m.14674

m.14667–14707 of the revised Cambridge Reference Sequence (NC_012920.1); the boxed base is m.14687 A→G.

37 genes from Ensembl (rCRS numbering, matched to MITOMAP’s Gene Loci); landmarks and disease alleles from MITOMAP (CC BY 3.0). Circular layout after MitoWheel.

Open Research Assistant for MT-TE →

External Resources

Franklin (Genoox)

AI-powered curation

MITOMAP

mtDNA variant database · expect a security check

VarSome

Variant interpretation · expect a security check

OMIM

Gene & phenotype

gnomAD

mtDNA frequencies (v3.1)

UCSC Browser

Genome browser

m.14687A>G

Resolving variant against ClinVar, gnomAD and Ensembl…

MT-TE:m.14687A>G

Where it sits in the mitochondrial genome

Population Allele Frequencies

External Resources

MT-TE:m.14687A>G

Where it sits in the mitochondrial genome

Population Allele Frequencies

External Resources