Genes associated with “hereditary spastic paraplegia”
Some sources returned errors (2)
omim: Error: OMIM search: 429
omimClinSyn: Error: OMIM CS: 429
How are genes scored? (0–100 composite)
Strong Candidates
58 genesDDHD domain containing 1
hereditary spastic paraplegia 28
glucosylceramidase beta 2
hereditary spastic paraplegia 46
SPG11 vesicle trafficking associated, spatacsin
hereditary spastic paraplegia 11
fatty acid 2-hydroxylase
hereditary spastic paraplegia 35
5'-nucleotidase, cytosolic II
hereditary spastic paraplegia 45
spastin
hereditary spastic paraplegia 4
ectonucleoside triphosphate diphosphohydrolase 1
hereditary spastic paraplegia 64
adaptor related protein complex 5 subunit zeta 1
hereditary spastic paraplegia 48
cytochrome P450 family 2 subfamily U member 1
hereditary spastic paraplegia 56
X-linked hydrocephalus with stenosis of the aqueduct of Sylvius
hereditary spastic paraplegia 26
Pelizeaus-Merzbacher spectrum disorder
Spastic paraplegia
hereditary spastic paraplegia 8
hereditary spastic paraplegia 61
Spastic paraplegia
hereditary spastic paraplegia 7
hereditary spastic paraplegia 3A
hereditary spastic paraplegia 49
ER lipid raft associated 1
trichomegaly-retina pigmentary degeneration-dwarfism syndrome
hereditary spastic paraplegia 73
hereditary spastic paraplegia 17
hereditary spastic paraplegia 54
early-onset progressive neurodegeneration-blindness-ataxia-spasticity syndrome
hereditary spastic paraplegia 5A
hereditary spastic paraplegia 31
hereditary spastic paraplegia 15
spastic paraplegia, intellectual disability, nystagmus, and obesity
hereditary spastic paraplegia 51
infantile-onset ascending hereditary spastic paralysis
hereditary spastic paraplegia 44
hereditary spastic paraplegia 10
autosomal recessive spastic paraplegia type 78
autosomal recessive complex spastic paraplegia type 9B
hereditary spastic paraplegia 74
hereditary spastic paraplegia 77
Troyer syndrome
hereditary spastic paraplegia 52
hereditary spastic paraplegia 72
hereditary spastic paraplegia 47
adrenoleukodystrophy
Allan-Herndon-Dudley syndrome
neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities
spastic paraplegia 80, autosomal dominant
mast syndrome
hereditary spastic paraplegia 6
kinesin family member 1C
hereditary spastic paraplegia 12
HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1
glutamic--pyruvic transaminase 2
hereditary spastic paraplegia 63
autosomal recessive spastic paraplegia type 76
phosphate cytidylyltransferase 2, ethanolamine
Consider
23 geneshereditary spastic paraplegia 43
Aicardi-Goutieres syndrome 2
spastic paraplegia 91, autosomal dominant, with or without cerebellar ataxia
spastic paraplegia 85, autosomal recessive
spastic paraplegia 84, autosomal recessive
hypomyelinating leukodystrophy 4
dystonia 9
syndromic X-linked intellectual disability Claes-Jensen type
ornithine translocase deficiency
adult polyglucosan body disease
neurodevelopmental disorder with spastic quadriplegia and brain abnormalities with or without seizures
hereditary spastic paraplegia 53
hereditary sensory and autonomic neuropathy with spastic paraplegia
hereditary spastic paraplegia 42
spastic paraplegia 86, autosomal recessive
Waardenburg syndrome type 3
spastic ataxia 1
giant axonal neuropathy 1
pyruvate dehydrogenase E3-binding protein deficiency
ichthyotic keratoderma, spasticity, hypomyelination, and dysmorphic facial features
Possible
15 genes — click to expand
developmental and epileptic encephalopathy, 4
X-linked intellectual disability-psychosis-macroorchidism syndrome
peroxisome biogenesis disorder 10B
hereditary spastic paraplegia 55
spastic paraplegia, optic atropy, and neuropathy
leukodystrophy, hypomyelinating, 23, with ataxia, deafness, liver dysfunction, and dilated cardiomyopathy
cobblestone lissencephaly without muscular or ocular involvement
spastic paraplegia 93, autosomal recessive
Related phenotype searches
Data aggregated from HPO/Monarch, ClinVar, OMIM (phenotypes + clinical synopsis), Open Targets, PanelApp, Phen2Gene, and Gene2Phenotype. Click a gene to view full details.