ZNF670

Chr 1

zinc finger protein 670

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within lipid metabolic process. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

151
ClinVar variants
72
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryZNF670
📋
ClinVar Variants
72 Pathogenic / Likely Pathogenic· 72 VUS of 151 total submissions
Some data sources returned errors (1)

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

151 submitted variants in ClinVar

Classification Summary

Pathogenic66
Likely Pathogenic6
VUS72
Likely Benign6
Benign1
66
Pathogenic
6
Likely Pathogenic
72
VUS
6
Likely Benign
1
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
66
0
66
Likely Pathogenic
0
0
6
0
6
VUS
0
55
17
0
72
Likely Benign
0
2
4
0
6
Benign
0
0
1
0
1
Total057940151

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

ZNF670 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →