ZNF475

Chr 5

zinc finger protein 475

NCBI Gene: 100505841ENSG00000250803UniProt: A0A1B0GTH9

Predicted to enable zinc ion binding activity. [provided by Alliance of Genome Resources, Jul 2025]

11
ClinVar variants
10
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— ZNF475
📋
ClinVar Variants
10 Pathogenic / Likely Pathogenic· 1 VUS of 11 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

11 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic10
VUS1
10
Pathogenic
1
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————10
Likely Pathogenic
————0
VUS
————1
Likely Benign
————0
Benign
————0
Total—11

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

ZNF475 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype Relationships

1 OMIM entry

OMIM
Clinical Literature
Landmark / reviewRecent case evidence

No publications found for ZNF475

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools