ZNF337
Chr 20zinc finger protein 337
This gene encodes a zinc finger domain containing protein. The function of this protein has yet to be determined. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2014]
ResearchGenerating clinical summary…
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Tolerant — LoF & missense variants common in population
LoF Constraint?
1.62LOEUF
pLI 0.004
Z-score 0.54
OE 0.75 (0.36–1.62)
Highly tolerant — LoF variants common in population
Missense Constraint?
-0.45Z-score
OE missense 1.06 (0.98–1.15)
418 obs / 392.8 exp
Tolerant to missense variation
Observed / Expected Ratios?
LoF OE?0.75 (0.36–1.62)
0≤0.351.4
Missense OE?1.06 (0.98–1.15)
0≤0.61.4
Synonymous OE?1.08
0≤1.21.6
LoF obs/exp: 4 / 5.4Missense obs/exp: 418 / 392.8Syn Z: -0.76
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
ZNF337 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →External Resources
Links to major genomics databases and tools