XLID98

Chr XXLD

neurite extension and migration factor

Also known as: KIAA2022, KIDLIA, MRX98, XLID98, XPN

This gene is disrupted by an X chromosome inversion that also affects a G-protein coupled purinergic receptor gene in the pseudoautosomal region. Mutations cause X-linked intellectual developmental disorder with an X-linked dominant inheritance pattern. The specific protein function remains unclear as the gene was identified through chromosomal rearrangement analysis rather than direct functional studies.

Summary from RefSeq, OMIM
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Primary Disease Associations & Inheritance

Intellectual developmental disorder, X-linked 98MIM #300912
XLD
0
Active trials
0
Pubs (1 yr)
0
P/LP submissions
P/LP missense
LOEUF
Mechanism
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/XLID98?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

XLID98 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
PubTator3
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Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found