VN1R5

Chr 1

vomeronasal 1 receptor 5 (gene/pseudogene)

Also known as: V1RL5

NCBI Gene: 317705ENSG00000197617UniProt: Q7Z5H4

Predicted to enable pheromone receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway and response to pheromone. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

81
ClinVar variants
71
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— VN1R5
📋
ClinVar Variants
71 Pathogenic / Likely Pathogenic· 10 VUS of 81 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

81 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic65
Likely Pathogenic6
VUS10
65
Pathogenic
6
Likely Pathogenic
10
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
————65
Likely Pathogenic
————6
VUS
————10
Likely Benign
————0
Benign
————0
Total—81

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

VN1R5 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

OMIM

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Top 5 resultsSearch Europe PMC ↗

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools