TTTY6B

Chr Y

testis expressed transcript, Y-linked 6B

Also known as: LINC00128, NCRNA00128, TTTY6, TTY6

The protein function and clinical significance of TTTY6B are not well established based on the available data. This gene is located on the Y chromosome and would follow patrilineal inheritance patterns, but no associated diseases or phenotypes have been definitively characterized. Further research is needed to determine its clinical relevance in pediatric neurology.

Summary from RefSeq
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0
Active trials
0
Pubs (1 yr)
75
P/LP submissions
P/LP missense
LOEUF
Mechanism
Clinical SummaryTTTY6B
📋
ClinVar Variants
75 unique Pathogenic / Likely Pathogenic· 13 VUS of 98 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

98 submitted variants in ClinVar

Classification Summary

Pathogenic72
Likely Pathogenic3
VUS13
Likely Benign8
Benign2
72
Pathogenic
3
Likely Pathogenic
13
VUS
8
Likely Benign
2
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
72
Likely Pathogenic
3
VUS
13
Likely Benign
8
Benign
2
Total98

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TTTY6B · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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