TTTY6

Chr Y

testis expressed transcript, Y-linked 6

Also known as: LINC00127, NCRNA00127, TTTY6A, TTY6

Based on the provided information, I cannot write a clinical gene summary for TTTY6. The RefSeq data only describes the chromosomal location and copy number but provides no information about protein function, associated diseases, inheritance patterns, or clinical phenotypes necessary for a pediatric neurogenetics summary.

Summary from RefSeq
Research Assistant →
0
Active trials
0
Pubs (1 yr)
71
P/LP submissions
P/LP missense
LOEUF
Mechanism
Clinical SummaryTTTY6
📋
ClinVar Variants
71 unique Pathogenic / Likely Pathogenic· 11 VUS of 92 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

92 submitted variants in ClinVar

Classification Summary

Pathogenic68
Likely Pathogenic3
VUS11
Likely Benign8
Benign2
68
Pathogenic
3
Likely Pathogenic
11
VUS
8
Likely Benign
2
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
68
Likely Pathogenic
3
VUS
11
Likely Benign
8
Benign
2
Total92

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TTTY6 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found