TTTY5

Chr Y

testis expressed transcript, Y-linked 5

Also known as: LINC00126, NCRNA00126, TTY5

TTTY5 is located on the Y chromosome and encodes a testis-specific transcript of unknown function. Currently, no Mendelian diseases have been definitively associated with mutations in this gene. This gene follows Y-linked inheritance, being passed from father to son.

Summary from RefSeq
Research Assistant →
0
Active trials
0
Pubs (1 yr)
75
P/LP submissions
P/LP missense
LOEUF
Mechanism
Clinical SummaryTTTY5
📋
ClinVar Variants
75 unique Pathogenic / Likely Pathogenic· 14 VUS of 101 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

101 submitted variants in ClinVar

Classification Summary

Pathogenic72
Likely Pathogenic3
VUS14
Likely Benign8
Benign4
72
Pathogenic
3
Likely Pathogenic
14
VUS
8
Likely Benign
4
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
72
Likely Pathogenic
3
VUS
14
Likely Benign
8
Benign
4
Total101

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TTTY5 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Open Research Assistant →
Key Publications
Landmark & review papers · by relevance
PubMed
Top 1 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found