TTTY4B

Chr Y

testis expressed transcript, Y-linked 4B

Also known as: LINC00124, NCRNA00124

TTTY4B is located on the Y chromosome within a palindromic repeat region, with three copies present in the human genome. No established disease associations or clinical phenotypes have been reported for mutations in this gene. The inheritance pattern would be patrilineal (father to son transmission) due to its Y-chromosomal location.

Summary from RefSeq
Research Assistant →
0
Active trials
0
Pubs (1 yr)
77
P/LP submissions
P/LP missense
LOEUF
Mechanism
Clinical SummaryTTTY4B
📋
ClinVar Variants
77 unique Pathogenic / Likely Pathogenic· 19 VUS of 106 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

106 submitted variants in ClinVar

Classification Summary

Pathogenic74
Likely Pathogenic3
VUS19
Likely Benign7
Benign3
74
Pathogenic
3
Likely Pathogenic
19
VUS
7
Likely Benign
3
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
74
Likely Pathogenic
3
VUS
19
Likely Benign
7
Benign
3
Total106

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TTTY4B · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
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Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
PubTator3
Top 2 full-text resultsSearch PubTator3 ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found