TTTY4
Chr Ytestis expressed transcript, Y-linked 4
Also known as: LINC00123, NCRNA00123, TTTY4A, TTY4
TTTY4 encodes a Y chromosome-specific transcript of unknown function that is expressed exclusively in males. The clinical significance of mutations in this gene has not been established, and no specific disease associations have been reported in the medical literature. This gene follows Y-linked inheritance, being passed from father to son.
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
106 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 76 |
Likely Pathogenic | — | — | — | — | 4 |
VUS | — | — | — | — | 15 |
Likely Benign | — | — | — | — | 10 |
Benign | — | — | — | — | 1 |
| Total | — | 106 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
TTTY4 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools