TTTY22

Chr Y

testis expressed transcript, Y-linked 22

Also known as: NCRNA00147

I cannot provide a clinical summary for TTTY22 as no functional or clinical information has been provided in the data below the gene name. This gene appears to be from the Y chromosome based on the "TTTY" prefix, but without specific information about protein function, associated diseases, or inheritance patterns, I cannot generate an accurate clinical summary following the guidelines.

Clinical SummaryTTTY22
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ClinVar Variants
52 unique Pathogenic / Likely Pathogenic· 4 VUS of 57 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

57 submitted variants in ClinVar

Classification Summary

Pathogenic50
Likely Pathogenic2
VUS4
Likely Benign1
50
Pathogenic
2
Likely Pathogenic
4
VUS
1
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
50
Likely Pathogenic
2
VUS
4
Likely Benign
1
Benign
0
Total57

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TTTY22 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Open Research Assistant →
Key Publications
Landmark & review papers · by relevance
PubMed
Top 3 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found