TTTY1B

Chr Y

testis expressed transcript, Y-linked 1B

I cannot provide a clinical summary for TTTY1B as no functional or clinical information has been provided in the data below this request. The gene appears to be located on the Y chromosome based on its name, but without specific information about protein function, associated diseases, or inheritance patterns, I cannot write an accurate clinical summary following the strict requirements to use only the provided information.

Clinical SummaryTTTY1B
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ClinVar Variants
57 unique Pathogenic / Likely Pathogenic· 6 VUS of 72 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

72 submitted variants in ClinVar

Classification Summary

Pathogenic55
Likely Pathogenic2
VUS6
Likely Benign8
55
Pathogenic
2
Likely Pathogenic
6
VUS
8
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
55
Likely Pathogenic
2
VUS
6
Likely Benign
8
Benign
0
Total71

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TTTY1B · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Open Research Assistant →
Key Publications
Landmark & review papers · by relevance
PubMed
Top 1 results · since 2015Search PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found