TTTY17A

Chr Y

testis expressed transcript, Y-linked 17A

Also known as: NCRNA00140, TTTY17

Based on the provided information, I cannot write a clinical gene summary for TTTY17A. The RefSeq description only indicates this is one of three copies of a gene located on chromosome Y, but provides no information about protein function, associated diseases, or clinical phenotypes. Additional clinical and functional data would be needed to create an informative summary for a pediatric neurogenetics portal.

OMIMResearchSummary from RefSeq
Clinical SummaryTTTY17A
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ClinVar Variants
80 unique Pathogenic / Likely Pathogenic· 14 VUS of 105 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

105 submitted variants in ClinVar

Classification Summary

Pathogenic76
Likely Pathogenic4
VUS14
Likely Benign10
Benign1
76
Pathogenic
4
Likely Pathogenic
14
VUS
10
Likely Benign
1
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
76
Likely Pathogenic
4
VUS
14
Likely Benign
10
Benign
1
Total105

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TTTY17A · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Open Research Assistant →
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found