TSGA10IP

Chr 11

testis specific 10 interacting protein

Also known as: FAM161C

Predicted to be involved in cilium organization. Predicted to be located in cytoskeleton. Predicted to be active in photoreceptor connecting cilium. [provided by Alliance of Genome Resources, Jul 2025]

121
ClinVar variants
10
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryTSGA10IP
📋
ClinVar Variants
10 Pathogenic / Likely Pathogenic· 103 VUS of 121 total submissions
Some data sources returned errors (1)

clinvar: Error: NCBI fetch failed: 429 https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

121 submitted variants in ClinVar

Classification Summary

Pathogenic8
Likely Pathogenic2
VUS103
Likely Benign8
8
Pathogenic
2
Likely Pathogenic
103
VUS
8
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
8
0
8
Likely Pathogenic
0
0
2
0
2
VUS
0
100
3
0
103
Likely Benign
0
8
0
0
8
Benign
0
0
0
0
0
Total0108130121

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TSGA10IP · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →