TRS-AGA2-6

Chr 17

tRNA-Ser (anticodon AGA) 2-6

Also known as: TRNAS14, TRS-AGA2-1

NCBI Gene: 100189184
17
ClinVar variants
7
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— TRS-AGA2-6
📋
ClinVar Variants
7 Pathogenic / Likely Pathogenic· 10 VUS of 17 total submissions
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/TRS-AGA2-6?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

17 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic7
VUS10
7
Pathogenic
10
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
0
0
7
0
7
Likely Pathogenic
0
0
0
0
0
VUS
0
0
10
0
10
Likely Benign
0
0
0
0
0
Benign
0
0
0
0
0
Total0017017

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TRS-AGA2-6 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype Relationships

1 OMIM entry

OMIM
Clinical Literature
Landmark / reviewRecent case evidence

No publications found for TRS-AGA2-6

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools