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TRR-TCT3-1

Chr 9

tRNA-Arg (anticodon TCT) 3-1

Also known as: TRNAR12, TRR-TCT3-2

I don't see any information provided about the TRR-TCT3-1 gene, including its protein function, associated diseases, or inheritance pattern. Without supporting data about what this gene does, what conditions result from mutations, and how it's inherited, I cannot write a clinical summary following the strict rules requiring only evidence-based information.

Clinical SummaryTRR-TCT3-1
📋
ClinVar Variants
19 unique Pathogenic / Likely Pathogenic· 1 VUS of 20 total submissions
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/TRR-TCT3-1?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

20 submitted variants in ClinVar

Classification Summary

Pathogenic19
VUS1
19
Pathogenic
1
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
19
Likely Pathogenic
0
VUS
1
Likely Benign
0
Benign
0
Total20

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TRR-TCT3-1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

3D Protein StructureAlphaFold

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Open Research Assistant →
Full-Text Mentions
NLP-detected gene mentions in article bodies · via PubTator3
PubTator3
Top 1 full-text resultsSearch PubTator3 ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found