TRN-GTT24-1

Chr 1

tRNA-Asn (anticodon GTT) 24-1

This record represents a tRNA model predicted using tRNAscan-SE (Lowe, T.M. and Eddy, S.R. 1997. Nucleic Acids Res. 25:955-964, PubMed 9023104).

57
ClinVar variants
53
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryTRN-GTT24-1
📋
ClinVar Variants
53 Pathogenic / Likely Pathogenic· 2 VUS of 57 total submissions
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/TRN-GTT24-1?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

57 submitted variants in ClinVar

Classification Summary

Pathogenic47
Likely Pathogenic6
VUS2
Benign1
Conflicting1
47
Pathogenic
6
Likely Pathogenic
2
VUS
1
Benign
1
Conflicting

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
47
Likely Pathogenic
6
VUS
2
Likely Benign
0
Benign
1
Conflicting
1
Total57

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TRN-GTT24-1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.