TRN-GTT2-1

Chr 1

tRNA-Asn (anticodon GTT) 2-1

Also known as: RNN, TRN, TRN1, TRNAN1, TRNAN5

60
ClinVar variants
59
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryTRN-GTT2-1
📋
ClinVar Variants
59 Pathogenic / Likely Pathogenic· 1 VUS of 60 total submissions
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/TRN-GTT2-1?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

60 submitted variants in ClinVar

Classification Summary

Pathogenic46
Likely Pathogenic13
VUS1
46
Pathogenic
13
Likely Pathogenic
1
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
46
Likely Pathogenic
13
VUS
1
Likely Benign
0
Benign
0
Total60

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TRN-GTT2-1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →