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TRL-TAA1-1
Chr 6tRNA-Leu (anticodon TAA) 1-1
Also known as: TRNAL29
I notice that you've provided the gene symbol "TRL-TAA1-1" but haven't included the supporting data that your instructions specify I must use (protein function, associated diseases, inheritance pattern, constraint metrics, etc.). Without this foundational information, I cannot write an accurate clinical summary following your strict rules about only using provided data. Could you please provide the relevant clinical and functional data for TRL-TAA1-1 so I can craft an appropriate 2-3 sentence summary for your pediatric neurogenetics portal?
Some data sources returned errors (2)
ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/TRL-TAA1-1?content-type=application/json&expand=1
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
5 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 5 |
Likely Pathogenic | — | — | — | — | 0 |
VUS | — | — | — | — | 0 |
Likely Benign | — | — | — | — | 0 |
Benign | — | — | — | — | 0 |
| Total | — | 5 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
TRL-TAA1-1 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools