TRGV5

Chr 7

T cell receptor gamma variable 5

Also known as: TCRGV5, V1S5

Predicted to be involved in adaptive immune response and innate immune response. Predicted to be located in plasma membrane. Predicted to be part of T cell receptor complex. Predicted to be active in external side of plasma membrane. [provided by Alliance of Genome Resources, Jul 2025]

9
ClinVar variants
7
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryTRGV5
📋
ClinVar Variants
7 Pathogenic / Likely Pathogenic of 9 total submissions
Some data sources returned errors (1)

clinvar: Error: NCBI fetch failed: 429 https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

9 submitted variants in ClinVar

Classification Summary

Pathogenic7
Likely Benign2
7
Pathogenic
2
Likely Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
7
Likely Pathogenic
0
VUS
0
Likely Benign
2
Benign
0
Total9

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TRGV5 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →