TRERNA1

Chr 20

translation regulatory long non-coding RNA 1

Also known as: LINC00651, MEF, treRNA

I cannot provide a clinical summary for TRERNA1 as no information about this gene's protein function, associated diseases, or inheritance pattern was provided in the data below the instructions. To write an accurate clinical summary following the specified guidelines, I would need details about what protein this gene encodes, what conditions result from mutations, and the inheritance pattern.

0
Active trials
2
Pubs (1 yr)
10
P/LP submissions
P/LP missense
LOEUF
Mechanism
Clinical SummaryTRERNA1
📋
ClinVar Variants
10 unique Pathogenic / Likely Pathogenic· 2 VUS of 12 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

12 submitted variants in ClinVar

Classification Summary

Pathogenic7
Likely Pathogenic3
VUS2
7
Pathogenic
3
Likely Pathogenic
2
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
7
Likely Pathogenic
3
VUS
2
Likely Benign
0
Benign
0
Total12

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TRERNA1 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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