TRE-TTC2-2

Chr 15

tRNA-Glu (anticodon TTC) 2-2

Also known as: TRNAE11

152
ClinVar variants
151
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryTRE-TTC2-2
📋
ClinVar Variants
151 Pathogenic / Likely Pathogenic· 1 VUS of 152 total submissions
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/TRE-TTC2-2?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

152 submitted variants in ClinVar

Classification Summary

Pathogenic150
Likely Pathogenic1
VUS1
150
Pathogenic
1
Likely Pathogenic
1
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
150
Likely Pathogenic
1
VUS
1
Likely Benign
0
Benign
0
Total152

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TRE-TTC2-2 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.