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TRE-TTC2-1
Chr 13tRNA-Glu (anticodon TTC) 2-1
Also known as: TRNAE7
I don't have sufficient information about the TRE-TTC2-1 gene to write a clinical summary following the strict rules provided. The gene name appears to reference a tRNA gene (TRE likely indicates tryptophan tRNA), but without specific data about its protein function, associated diseases, inheritance patterns, or clinical phenotypes, I cannot provide an accurate clinical summary that meets the requirements of using only supported information.
Some data sources returned errors (2)
ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/TRE-TTC2-1?content-type=application/json&expand=1
gnomad: Error: Gene not found
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
28 submitted variants in ClinVar
Classification Summary
Curated Variants Distribution
Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable
| Classification | LoF | Missense + Inframe | Non-coding | Synonymous | Total |
|---|---|---|---|---|---|
Pathogenic | — | — | — | — | 28 |
Likely Pathogenic | — | — | — | — | 0 |
VUS | — | — | — | — | 0 |
Likely Benign | — | — | — | — | 0 |
Benign | — | — | — | — | 0 |
| Total | — | 28 | |||
Counts from ClinVar esearch · Updated hourly
View in ClinVar →Protein Context — Lollipop Plot
TRE-TTC2-1 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No publications found for TRE-TTC2-1
External Resources
Links to major genomics databases and tools