TRBV17

Chr 7

T cell receptor beta variable 17 (non-functional)

Also known as: TCRBV17S1, TCRBV26S1P

Predicted to be involved in cell surface receptor signaling pathway. Predicted to be part of T cell receptor complex. Predicted to be active in plasma membrane. [provided by Alliance of Genome Resources, Apr 2025]

30
ClinVar variants
21
Pathogenic / LP
pLI score
0
Active trials
Clinical SummaryTRBV17
📋
ClinVar Variants
21 Pathogenic / Likely Pathogenic· 2 VUS of 30 total submissions
Some data sources returned errors (1)

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

30 submitted variants in ClinVar

Classification Summary

Pathogenic20
Likely Pathogenic1
VUS2
Likely Benign5
Benign2
20
Pathogenic
1
Likely Pathogenic
2
VUS
5
Likely Benign
2
Benign

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
20
Likely Pathogenic
1
VUS
2
Likely Benign
5
Benign
2
Total30

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TRBV17 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →