TP53TG3

Chr 16

TP53 target 3

Also known as: P53TG3, TP53TG3A

NCBI Gene: 24150 ENSG00000183632 UniProt: Q9ULZ0 OMIM: 617482

TP53TG3 encodes a protein that may participate in p53-mediated signaling pathways and is located in both the cytoplasm and nucleus. Currently, no specific diseases have been definitively associated with mutations in this gene in the provided clinical databases. The inheritance pattern and clinical significance of TP53TG3 variants remain to be established.

OMIM ResearchSummary from RefSeq, UniProt

Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Jul 2025]

OMIM ResearchGenerating clinical summary…

Clinical Summary— TP53TG3

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ClinVar Variants

3 total variants — no pathogenic classifications of 3 total submissions

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Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

3 submitted variants in ClinVar

ClinVar

Classification Summary

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

Classification	LoF	Missense + Inframe	Non-coding	Synonymous
Pathogenic	—	—	—	—
Likely Pathogenic	—	—	—	—
VUS	—	—	—	—
Likely Benign	—	—	—	—
Benign	—	—	—	—
Total	—

Counts from ClinVar esearch · Updated hourly

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7 pathogenic / likely-pathogenic (of 22) ClinVar copy-number / structural variants overlap TP53TG3 — these span large chromosomal regions, not the gene specifically, and are excluded from the counts above. Explore in CNV tools →