TNFRSF19
Chr 13TNF receptor superfamily member 19
Also known as: TAJ, TAJ-alpha, TRADE, TROY
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is highly expressed during embryonic development. It has been shown to interact with TRAF family members, and to activate JNK signaling pathway when overexpressed in cells. This receptor is capable of inducing apoptosis by a caspase-independent mechanism, and it is thought to play an essential role in embryonic development. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
Some data sources returned errors (2)
gnomad: Error: gnomAD API error: 400
omim: Error: OMIM fetch failed: 429
Population Genetics & Constraint
Constraint data not available from gnomAD.
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
TNFRSF19 · protein map & ClinVar variants
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External Resources
Links to major genomics databases and tools
Clinical Trials
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