TMEM278

Chr 1

transmembrane protein 278

Also known as: TMEM88B

The protein is predicted to negatively regulate canonical Wnt signaling and localize to the plasma membrane. No human diseases have been definitively associated with TMEM278 mutations based on the available information. The inheritance pattern and clinical phenotypes remain to be established.

Summary from RefSeq
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0
Active trials
0
Pubs (1 yr)
0
P/LP submissions
P/LP missense
LOEUF
Mechanism
Some data sources returned errors (2)

ensembl: Error: Ensembl fetch failed: 400 for https://rest.ensembl.org/lookup/symbol/homo_sapiens/TMEM278?content-type=application/json&expand=1

gnomad: Error: Gene not found

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

0 submitted variants in ClinVar

Protein Context — Lollipop Plot

TMEM278 · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

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Clinical Literature
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No publications found for TMEM278