TLE1-DT

Chr 9

TLE1 divergent transcript

I cannot write a clinical summary for TLE1-DT based on the provided information. No data about the protein function, associated diseases, inheritance patterns, or pathogenic mechanisms was included in your request. Please provide the relevant clinical and molecular information needed to create an accurate gene summary.

0
Active trials
0
Pubs (1 yr)
13
P/LP submissions
P/LP missense
LOEUF
Mechanism
Clinical SummaryTLE1-DT
📋
ClinVar Variants
13 unique Pathogenic / Likely Pathogenic· 1 VUS of 14 total submissions

Population Genetics & Constraint

Constraint data not available from gnomAD.

ClinVar Variant Classifications

14 submitted variants in ClinVar

Classification Summary

Pathogenic13
VUS1
13
Pathogenic
1
VUS

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories· variant type breakdown unavailable

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
13
Likely Pathogenic
0
VUS
1
Likely Benign
0
Benign
0
Total14

Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TLE1-DT · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →
Clinical Literature
Open Research Assistant →
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC

No open access results found