TH2LCRR

Chr 5

T helper type 2 locus control region associated RNA

NCBI Gene: 101927761ENSG00000223442
520
ClinVar variants
50
Pathogenic / LP
—
pLI score
0
Active trials
Clinical Summary— TH2LCRR
📋
ClinVar Variants
50 Pathogenic / Likely Pathogenic· 291 VUS of 520 total submissions

Population Genetics & Constraint

gnomAD

Constraint data not available from gnomAD.

ClinVar Variant Classifications

520 submitted variants in ClinVar

ClinVar

Classification Summary

Pathogenic22
Likely Pathogenic28
VUS291
Likely Benign154
Benign1
Conflicting24
22
Pathogenic
28
Likely Pathogenic
291
VUS
154
Likely Benign
1
Benign
24
Conflicting

Curated Variants Distribution

Classified variants from ClinVar · 5 ACMG categories

ClassificationLoFMissense + InframeNon-codingSynonymousTotal
Pathogenic
12
0
10
0
22
Likely Pathogenic
18
1
9
0
28
VUS
11
250
29
1
291
Likely Benign
1
1
59
93
154
Benign
0
0
0
1
1
Conflicting
—24
Total4225210795520

LoF = frameshift, stop gained/lost, canonical splice · Counts from ClinVar esearch · Updated hourly

View in ClinVar →

Protein Context — Lollipop Plot

TH2LCRR · protein map & ClinVar variants

Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.

OMIM — Genotype-Phenotype

OMIM

No OMIM entries found.

Clinical Literature
Landmark / reviewRecent case evidence
Key Publications
Landmark & review papers · by relevance
PubMed
Top 10 resultsSearch PubMed ↗
Recent Gene-Specific Literature
Gene in title · MEDLINE · newest first
Europe PMC
Top 5 resultsSearch Europe PMC ↗

Clinical Trials

Active and recruiting trials from ClinicalTrials.gov

ClinicalTrials.gov

No active trials found for this gene.

Search ClinicalTrials.gov →

External Resources

Links to major genomics databases and tools