TCEAL3
Chr Xtranscription elongation factor A like 3
Also known as: WEX8
The protein is a nuclear phosphoprotein that modulates transcription in a promoter context-dependent manner and is part of the transcription elongation factor A-like gene family. Mutations cause X-linked intellectual disability, and the gene shows moderate constraint against loss-of-function variants. The gene follows X-linked inheritance patterns.
Population Genetics & Constraint
gnomAD v4 — loss-of-function & missense intolerance
Typical tolerance to LoF variation
Mild missense constraint
ClinVar Variant Classifications
0 submitted variants in ClinVar
Protein Context — Lollipop Plot
TCEAL3 · protein map & ClinVar variants
Showing all ClinVar variants across the protein. Search a specific variant to highlight its position.
3D Protein StructureAlphaFold
External Resources
Links to major genomics databases and tools
Clinical Trials
Active and recruiting trials from ClinicalTrials.gov
No active trials found for this gene.
Search ClinicalTrials.gov →No open access results found
External Resources
Links to major genomics databases and tools